Cox-2 regulation by IL-1β through MAPKs: A comparison of nasal mucosa and nasal polyps fibroblasts from AIA patients

F. J. Garcia-Garcia, J. Roca-Ferrer, M. Pérez, I. Alobid, J. Mullol, C. Picado (Barcelona, Madrid, Spain)

Source: Annual Congress 2010 - COPD and asthma: models and human studies
Session: COPD and asthma: models and human studies
Session type: E-Communication Session
Number: 1987
Disease area: Airway diseases

Congress or journal article abstractE-poster

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
F. J. Garcia-Garcia, J. Roca-Ferrer, M. Pérez, I. Alobid, J. Mullol, C. Picado (Barcelona, Madrid, Spain). Cox-2 regulation by IL-1β through MAPKs: A comparison of nasal mucosa and nasal polyps fibroblasts from AIA patients. Eur Respir J 2010; 36: Suppl. 54, 1987

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Glucocorticoid therapy increases COX-2 gene expression in nasal polyps in vivo
Source: Eur Respir J 2009; 33: 502-508
Year: 2009



Increased expression of IL-19 in metaplastic epithelium of patients with chronic rhinosinusitis and nasal polyps
Source: Annual Congress 2011 - Epithelial cell biology
Year: 2011

NOTCH-1 activation sustains hyperexpression of IL-33 in the epithelium of nasal polyps
Source: International Congress 2017 – Systemic and airway biomarkers
Year: 2017

Role of IL-13Ra2 in modulating IL-13 induced MUC5AC and ciliary changes in healthy and CRSwNP mucosa
Source: International Congress 2019 – Novel insights from in vitro and in vivo models of lung disease
Year: 2019

Anti-proliferative and anti-inflammatory effect of glucocorticoids in nasal mucosa and nasal polyp fibroblasts
Source: Annual Congress 2010 - Novel cellular mechanisms in lung disease
Year: 2010


Recruitment of eosinophils and increased expression of mast cells tryptase in the bronchial mucosa of patients with allergic asthma
Source: Eur Respir J 2002; 20: Suppl. 38, 508s
Year: 2002

Intranasal steroids decrease eosinophils but not mucin expression in nasal polyps
Source: Eur Respir J 2004; 24 : 594-600
Year: 2004



Eotaxins expression in nasal mucosa in patients with asthma and seasonal rhinitis
Source: Annual Congress 2010 - Cell biology and immunology of lung disease
Year: 2010

Chemokine expression, apoptosis, and proliferation in the airway mucosa at steroid-mediated resolution of allergic rhinitis
Source: Eur Respir J 2003; 22: Suppl. 45, 32s
Year: 2003

Mechanisms responsible for glucocorticoid insensitivity in nasal mucosa and nasal polyps
Source: Annual Congress 2010 - COPD and asthma: models and human studies
Year: 2010


Wnt/ß-catenin signalling is upregulated in the COPD bronchial epithelium.
Source: International Congress 2019 – Novel mechanisms elucidated by translational studies of COPD
Year: 2019


Lipopolysacharide modulates glucocorticoid receptor function in nasal mucosa and polyp fibroblasts
Source: Annual Congress 2013 –Cell signalling and inflammation: what's new in 2013?
Year: 2013

Over-expression of Th17-related cytokines in bronchial and nasal submucosa in severe asthma
Source: Annual Congress 2012 - Trials in asthma: asthma exacerbations and severe asthma
Year: 2012


A transcriptomic comparison between nasal and bronchial airway epithelia from children.
Source: International Congress 2017 – Asthma genetics and genomics in patients and populations
Year: 2017

Effects of TNF-alpha on the human nasal mucosa in vivo
Source: Eur Respir J 2006; 28: Suppl. 50, 672s
Year: 2006

Relationship between allergen-induced increase of AHR to bradykinin, expression of the proliferation marker Ki-67 and eosinophils in bronchial mucosa of atopic asthmatics
Source: Annual Congress 2003 - Modulation of bronchial hyperreactivity and immune response in the airways
Year: 2003


Expression of mast cell tryptase in bronchial mucosa of asthmatic guinea pigs
Source: Eur Respir J 2002; 20: Suppl. 38, 512s
Year: 2002

Differences in nasal fluid levels of myeloperoxidase (MPO) and fucose after lavage with saline and histamine solutions, respectively, may indicate a neutrophil inflammation in the nasal mucosa in patients with COPD, and moreover, a glandular
Source: Eur Respir J 2002; 20: Suppl. 38, 93s
Year: 2002

Comparison of nasal and bronchial epithelial cell inflammatory phenotype
Source: Eur Respir J 2006; 28: Suppl. 50, 235s
Year: 2006

CCSP modulates inflammation in bronchial epithelium differentiated ex vivo from bronchial biopsy of COPD patients
Source: Annual Congress 2010 - Novel cellular mechanisms in lung disease
Year: 2010