Estimation of maximal work rate based on the six-minute walking test and fat-free mass in patients with COPD

V. Cavalheri, N. A. Hernandes, C. A. Camillo, V. S. Probst, D. Ramos, F. Pitta (Presidente Prudente, Londrina, Brazil)

Source: Annual Congress 2010 - Exercise training: new groups, new methods and outcomes
Session: Exercise training: new groups, new methods and outcomes
Session type: Thematic Poster Session
Number: 4882
Disease area: Airway diseases

Congress or journal article abstractE-poster

Abstract

Objective: To propose a predictive equation of cycle ergometry maximal work rate (Wmax) in patients with chronic obstructive pulmonary disease (COPD) based on the product of 6-minute walking test (6MWT) and fat-free mass (FFM), and to compare it with a previously proposed equation based on the work performed during the 6MWT (i.e., the product of 6MWT and body weight). Methods: Fifty-three patients with COPD (30 men; FEV1 45±15%predicted; BMI 27±5kg/m2) were submitted to spirometry, bioelectrical impedance, 6MWT and maximal cycle ergometry incremental test. Three Wmax were produced: the Wmax_real (obtained during the maximal cycle ergometry test), the estimated Wmax_6MWT*BW (obtained from the product of 6MWT and body weight) and the estimated Wmax_6MWT*FFM (obtained from the product of 6MWT and FFM). Results: The equation derived from a regression model to estimate Wmax_6MWT*FFM was: -27.9717 + 3.7792*(6MWT*FFM). Correlation of the Wmax_real was higher with Wmax_6MWT*FFM (r=0.65) than with Wmax_6MWT*BW (r=0.53). Furthermore, there was no difference between the estimated Wmax_6MWT*FFM (41[29-50]watts) and the Wmax_real (40[20-50]watts) (p=0.88), whereas Wmax_6MWT*BW (60[52-69]watts) showed significant overestimation in comparison to the Wmax_real (p<0.0001). Conclusion: In patients with COPD, maximal work rate in cycle ergometry is better estimated by the equation including the product of 6MWT and fat-free mass than by a previously proposed equation including the product of 6MWT and body weight.


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V. Cavalheri, N. A. Hernandes, C. A. Camillo, V. S. Probst, D. Ramos, F. Pitta (Presidente Prudente, Londrina, Brazil). Estimation of maximal work rate based on the six-minute walking test and fat-free mass in patients with COPD. Eur Respir J 2010; 36: Suppl. 54, 4882

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