Sputum MMP-12 concentration and enzyme activity in COPD and asthma in relation to smoking status and disease severity

R. Chaudhuri, I. Donnelly, C. Grierson, P. Lapan, J. Brady, L. Jolly, C. Weir, C. Messow, C. McSharry, M. Spears, D. Miller, N. Thomson (Glasgow, Dundee, United Kingdom; Collegeville, United States Of America)

Source: Annual Congress 2010 - Induced sputum in relation: a fresh look on phenotyping and monitoring
Session: Induced sputum in relation: a fresh look on phenotyping and monitoring
Session type: E-Communication Session
Number: 5497
Disease area: Airway diseases

Congress or journal article abstractE-poster

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
R. Chaudhuri, I. Donnelly, C. Grierson, P. Lapan, J. Brady, L. Jolly, C. Weir, C. Messow, C. McSharry, M. Spears, D. Miller, N. Thomson (Glasgow, Dundee, United Kingdom; Collegeville, United States Of America). Sputum MMP-12 concentration and enzyme activity in COPD and asthma in relation to smoking status and disease severity. Eur Respir J 2010; 36: Suppl. 54, 5497

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Proteolytic activity of sputum and serum in patients with COPD exacerbation in dependence on smoking
Source: Eur Respir J 2003; 22: Suppl. 45, 416s
Year: 2003

Leptin levels in induced sputum from patients with COPD are sensitive to smoking status
Source: Eur Respir J 2005; 26: Suppl. 49, 660s
Year: 2005

Systemic inflammation in COPD in relation to smoking status
Source: Virtual Congress 2020 – Smoking disease landscape: from inflammation to lung function and comorbidities
Year: 2020


CC10 and TIMP1 levels in induced sputum of smokers who developed chronic airflow impairment
Source: Annual Congress 2005 - Experimental approaches to the study of chronic cough and cigarette smoking
Year: 2005


The effect of smoking on the activity of inflammatory markers in patients with COPD
Source: Annual Congress 2013 –Tobacco use in different countries: crisis to disease
Year: 2013


Elevated sputum BPIFB1 levels correlate with progression of chronic obstructive pulmonary disease
Source: International Congress 2015 – Exploring mechanisms in obstructive airway diseases
Year: 2015


Contribution of TGFβ1 and TIMP2 to clinical activity of asthma and COPD
Source: Annual Congress 2011 - Novel mechanisms in lung injury
Year: 2011

Cytokines and MMP-9 level in serum and induced sputum of patients with suspicion of occupational COPD
Source: International Congress 2016 – Occupational and environmental exposures and biomarkers: human studies, animal data, and in vitro methods
Year: 2016

The tobacco smoking influence on parodontic inflammation in patients with COPD
Source: Eur Respir J 2007; 30: Suppl. 51, 167s
Year: 2007

Sputum biomarkers of inflammation in smokers and subjects with COPD
Source: Annual Congress 2013 –Systemic and airway biomarkers in respiratory diseases
Year: 2013


Induced sputum in asthma and COPD: meassuring type and inflammation activity
Source: Eur Respir J 2003; 22: Suppl. 45, 76s
Year: 2003

CD8+ve airway inflammation in COPD: The impact of smoking status
Source: Annual Congress 2003 - Cigarette smoke: how it does its dirty work
Year: 2003


COPD disease progression and airway inflammation: uncoupled by smoking cessation
Source: Eur Respir J 2005; 26: 764-766
Year: 2005


Impact of sputum bacteria on airway inflammation and health status in clinical stable COPD
Source: Eur Respir J 2004; 23: 685-691
Year: 2004



Serum hyaluronidase-1 is increased in COPD exacerbations and is associated with COPD severity and outcomes
Source: International Congress 2018 – Disease exacerbations from a molecular point of view
Year: 2018



Overexpression of chitotriosidase and YKL-40 in serum and sputum in healthy smokers and patients with  chronic obstructive pulmonary disease
Source: International Congress 2018 – Clinical determinants and biomarkers of COPD
Year: 2018




Decrease of physical activity in patients with COPD in the course of the disease
Source: Annual Congress 2012 - The best abstracts in chronic care
Year: 2012

Elevated circulating CTLA-4 level in patients with COPD is related to systemic inflammation and disease severity
Source: Annual Congress 2013 –COPD: markers and inflammation
Year: 2013



Bronchial inflammation without asthma symptoms, relation to low neutrophil activity in serum
Source: Eur Respir J 2002; 20: Suppl. 38, 143s
Year: 2002

Relationship between age, sex, duration of asthma, asthma severity and deterioration of lung function in asthmatic patients
Source: Eur Respir J 2001; 18: Suppl. 33, 33s
Year: 2001