Source: Annual Congress 2010 - Exercise training and pulmonary rehabilitation

Abstract

OBJECTIVE: Patients operated for lung cancer report functional deficits and poor quality of life. This study investigates short term effects of a rehabilitation programme on quality of life, physical performance and lung function in patients, who are radically operated for lung cancer.
DESIGN AND PATIENTS: A prospective, randomised, single blinded intervention, including 78 patients.
INTERVENTIONS: The intervention group (n= 40) participates in a 3 month out patient rehabilitation programme in groups, based on aerobic exercises, resistance training and dyspnoea management. Target intensity is 60- 80% of work capacity. Control group (n=38) receives one individual instruction in exercise training.
MEASUREMENTS: Health related quality of life (SF-36); physical performance (6 MWT); spirometri (FEV₁, FVC and FEV₁/FVC). Measurements are taken at baseline and after 4 months.
RESULTS: Preliminary results for 41 patients show slight improvements in all measurements for both groups. Differences between intervention and control group are: SF-36 PCS Physical Score 8% (16% vs 8 %), SF-36 MCS Mental Score -11% (5% vs 16%), FVC 4% (12% vs 8%). There are no differences in 6MWT and FEV₁. Subgroup analysis shows that patients in the intervention group not receiving adjuvant treatment have a higher perception of PCS than other patients. Women with secondary cancer are more likely to report poorer MCS, when compared to women with primary lung cancer or compared to men (-4% vs 10%, men 13%).
CONCLUSION: Participation in a rehabilitation programme improves the perception of health related physical performance. Women with secondary lung cancer tend to have a poorer score on mental health than other participants of both genders.

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Citations should be made in the following way:
B. Brocki, L. Rodkjær, V. Nekrasas, K. Due, C. Dethlefsen, J. Andreasen (Aalborg, Denmark). Rehabilitation after lung cancer operation – A randomised controlled study. Eur Respir J 2010; 36: Suppl. 54, 1940

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