Source: Annual Congress 2010 - Nocturnal cardiology: chronic heart failure, acute chest syndrome, coronary artery disease and collagen vascular disease
Disease area: Sleep and breathing disorders

Abstract

Background: Short sleep duration and impaired sleep quality have been linked with poor prognosis. The impact of reduced sleep efficiency (total sleep time/time in bed) in patients with chronic heart failure (CHF) is unknown. The objective of this observational study was to test the prognostic impact of sleep efficiency in patients with CHF.
Methods: We studied 296 CHF patients (median left ventricular ejection fraction 33%) who underwent in-lab polysomnography at the University of Regensburg between 06/2001 and 3/2009 to assess objective sleep quality, sleep related breathing disorders and periodic leg movement disorders.
Results: CHF patients were stratified in quartiles of sleep quality impairment (sleep efficiency ≥91%, ≥85 to <91%, ≥76 to <85% and<76%). During the median follow-up time of 47.5 months 77 deaths occurred. An increasing degree of sleep quality impairment was significantly related with a rise of mortality rates (20%, 26%, 30% and 40%, respectively; cox regression p=0.017; [figure 1]).

After accounting for potential confounders (cause of CHF, peak oxygen consumption, apnea-hypopnea index, positive airway pressure treatment) impaired sleep efficiency was still significantly associated with increased mortality (p=0,046).
Conclusion: Objectively assessed impairment of sleep quality is related with increased mortality risk in patients with CHF, independent of the severity of CHF and sleep apnea.

Rating:

Share or cite this content

Citations should be made in the following way:
N. Plappert, M. Krenn, R. Obermeier, A. Braune, A. Brandl-Novak, I. Haller, G. A. J. Riegger, M. Pfeifer, M. Arzt (Donaustauf, Germany). Impaired sleep quality is independently related with mortality in heart failure patients. Eur Respir J 2010; 36: Suppl. 54, 904

Member's Comments

No comment yet.

Related content which might interest you: Increased long-term mortality in heart failure due to sleep apnoea is not yet proven Source: Eur Respir J 2004; 23: 735-740 Year: 2004 The correlation between sleepiness, disease-specific quality of life and the prevalence of sleep related disorder in patients with congestive heart failure Source: Eur Respir J 2003; 22: Suppl. 45, 274s Year: 2003 Impaired pulmonary function and its association with clinical outcomes, exercise capacity and quality of life in children with congenital heart disease Source: Virtual Congress 2020 – Clinical year in review Year: 2020 Renal function impairment and prediction of sleep apnea in patients with high cardiovascular risk Source: Virtual Congress 2020 – Consequences for obstructive sleep apnoea and potential modalities for early identification Year: 2020 The severity of central sleep apnoea syndrome in patients with chronic congestive heart failure is dependent on the quality of medical treatment Source: Eur Respir J 2002; 20: Suppl. 38, 293s Year: 2002 Phenotypes related to long term renal function decline and mortality in adult OSA. Source: Virtual Congress 2020 – Treatment of obstructive sleep apnoea and its effects Year: 2020 Psychological factors in patients with right heart failure associated with COPD Source: International Congress 2019 – Pulmonary hypertension with lung diseases and experimental pulmonary hypertension Year: 2019 Evaluation of health related quality of life in patients with stable chronic respiratory failure Source: Eur Respir J 2004; 24: Suppl. 48, 66s Year: 2004 Alterations in cardiovascular function in COPD and heart failure patients with sarcopenia Source: Virtual Congress 2020 – Exploring exercise responses in respiratory diseases Year: 2020 Sleep quality of patients with acute respiratory failure, during hospitalization Source: Annual Congress 2009 - Control of breathing and respiratory disorders during sleep Year: 2009 Cardiac performance indices and neurohumoral activation in patients with stable chronic heart failure and sleep disordered breathing Source: Annual Congress 2009 - Pathogenesis of sleep-disordered breathing Year: 2009 Dyspnea sensation and health-related quality predict exacerbations, hospitalizations and mortality in patients with chronic respiratory failure receiving long-term oxygen therapy Source: Eur Respir J 2006; 28: Suppl. 50, 519s Year: 2006 Changes in heart rate variability during psychological stress in cardiorespiratory failure patients Source: Virtual Congress 2020 – Pulmonary embolism Year: 2020 The use of heart rate variability in detecting sleep disordered breathing in patients with heart failure Source: Eur Respir J 2004; 24: Suppl. 48, 564s Year: 2004 The impact of decreased 6MWT and exercise-induced desaturation on long-term survival and mortality related to Czech and Spanish phenotypes in patients with severe COPD Source: International Congress 2019 – Phenotypes and comorbidities of airway diseases Year: 2019 The relationship between autonomic modulation of heart rate variability and sleep breathing disorders in patient with chronic heart failure Source: Eur Respir J 2006; 28: Suppl. 50, 815s Year: 2006 Quality of life and functional capacity in heart failure patients Source: Annual Congress 2011 - Rehabilitation, outcome measures and effects Year: 2011 Assessment of aortic stiffness which is a new cardiovascular morbidity and mortality predictor in patients with obstructive sleep apnea syndrome and relation with severity of the disease Source: Eur Respir J 2006; 28: Suppl. 50, 814s Year: 2006 Cardiorespiratory monitoring in the diagnosis of sleep related breathing disorders in patients with stable heart failure Source: Eur Respir J 2002; 20: Suppl. 38, 293s Year: 2002 OSA as a cause of cardiovascular disease, including heart failure Source: ERS Conference Year: 2015