Source: Annual Congress 2010 - State of the art imaging
Disease area: Thoracic oncology

Abstract

Background: Regional health providers and policy makers (Cancer Care Ontario CCO and others) have determined PET/CT superior to conventional imaging (CI) in the solid organ staging (M) of operable non small cell lung cancer, (NSCLC) but have restricted access to PET/CT according to strict criteria. This prospective study was undertaken to determine if patients who do not meet CCO guidelines would similarly benefit from this preoperative investigation.
CCO published results of 337 patients average age 66 yrs half male . 23(14%) of 163 patients in PET/CT arm were correctly upstaged compared to 7% of the 157 patients who had CI (p=0.046). Therefore 7% of the patients avoided "inappropriate surgery".
Results: 54 patients with prsumed NSCLC at our centre, underwent PET/CT staging and not meet the CCO criteria and were selected on the bases of surgeon‘s discretion. 4 patients were excluded. 50 patients (24 male, 26 female) were included in the final analysis. PET-CT was supportive of all other investigations in 38 (76%); altered care by adding important new information in 7 (14%); and was misleading in 5 cases (8%).
Conclusion: This study mirors the CCO study. Preoperative staging with PET-CT for patients with lung cancer is a useful tool when applied based on surgeons discretion and can be as effective as when it is used based on the CCO guidelines.

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Citations should be made in the following way:
J. Miller, M. Rahimi-Darabad, G. Travis (Hamilton, Canada). PET-CT a useful staging tool for patients with non small lung cancer when applied based on surgeons‘ discretion as well as guidelines. Eur Respir J 2010; 36: Suppl. 54, 5288

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