Source: Annual Congress 2010 - Nocturnal cardiology: chronic heart failure, acute chest syndrome, coronary artery disease and collagen vascular disease
Disease area: Pulmonary vascular diseases, Sleep and breathing disorders

Abstract

Objective: Although the prevalence of sleep-disordered breathing (SDB) has been found to be high in patients with acute coronary syndrome (ACS), there is little knowledge about the persistence of SDB in ACS patients after the acute event. The aim of this study was to assess the time course of SDB in patients with ACS, during the acute event and after 1 and 6 months later, away from the CCU environment.
Patients and methods: Fifty two patients with first ever ACS and with preserved left ventricular function, who were not on sedation or inotropes, underwent a full polysomnography (PSG) in our sleep disorders unit, away from the CCU environment, within 3 days of the ACS. In patients with an apnea hypopnea index (AHI) >10/h, we performed a follow up PSG one and six months later.
Results: Twenty eight of 52 (54%) patients with an AHI>10/h were included in the study. There was a significant decrease in AHI 1 month after the acute event (13.9 ± 5.9 vs 19.7± 6.7, p=0.001), confirming the diagnosis of OSA in 22 of 28 patients (79%) and a more significant decrease 6 months later compared with the initial PSG (7.5± 4.6 vs 19.7± 6.7, p<0.05), confirming the diagnosis of OSA in only 6 of 28 patients (21%).
Conclusions: We have demonstrated a high prevalence of sleep apnoea in the acute myocardial ischemia setting, which did not persist, and AHI was significantly lower 6 months later, indicating that SDB abnormalities may be transient.

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I. Bouloukaki, E. Simantirakis, C. Mermigis, D. Arfanakis, S. Chrysostomakis, E. Kallergis, P. Vardas, E. Vlachaki, N. Siafakas, S. Schiza (Athens, Greece). Sleep disordered breathing in patients with acute coronary syndromes. Eur Respir J 2010; 36: Suppl. 54, 909

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