Simple logistic models in the development of a quality of life questionnaire specific for patients with chronic obstructive pulmonary disease
G. Bertolotti, M. Carone, G. Vidotto, M. Neri, F. Arpinelli, R. Testi, V. Bellia, C. F. Donner, P. Jones (Tradate, Verona, Italy; , ; London, United Kingdom)
Source: Annual Congress 2005 - Health status in COPD and asthma: its relevance in pulmonary rehabilitation
Disease area: Airway diseases
Abstract Aim . To develop a specific, reliable, and valid questionnaire to measure QoL in Italian COPD patients Method . A set of 124 items significant for Italian COPD patients was identified. We used the classical psychometric methods together with Simple Logistic Models (SLM) to analyze the items Subjects . Patients were recruited in 2 hospitals in North (n=62 patients, 69 years) and 1 in South Italy (n=34 patients, 69 years). All patients completed a General (GH) and Respiratory Health (RH) questionnaire Results. The model to reduced item was Response rate>75% - 14 items excluded; Response rate<20% and weak (<10%) association with GH% - 3 items excluded; Age shared variance 4% - 8 items excluded; Gender shared variance>4% - 8 items excluded; Centre shared variance>4 % - 2 items excluded. GH shared variance<4% - 48 items excluded; RH shared variance<4 % - 50 items excluded. 4 more items showed abnormal residual and/or Chi Square values for item-trait interaction in data analysis with SLM. The 43 items that meet the inclusion criteria have good levels of repeatability Conclusions . Using criteria of different levels of strictness, we have identified a set of items that have psychometric properties suitable for inclusion into the final version. Classical analysis and SLM could interact to produce short and reliable questionnaires
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G. Bertolotti, M. Carone, G. Vidotto, M. Neri, F. Arpinelli, R. Testi, V. Bellia, C. F. Donner, P. Jones (Tradate, Verona, Italy; , ; London, United Kingdom). Simple logistic models in the development of a quality of life questionnaire specific for patients with chronic obstructive pulmonary disease. Eur Respir J 2005; 26: Suppl. 49, 2048
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