Source: Annual Congress 2010 - Exercise training: new groups, new methods and outcomes
Disease area: Airway diseases

Abstract

Background: Maximal workload (Wmax) achieved during a cardiopulmonary exercise test (CPET) is frequently used to prescribe exercise training intensity in patients with COPD. Recently, Hill et al. (2008) and Luxton et al. (2008) proposed equations to estimate Wmax based on the 6-minute walking distance test (6MWT) and on the 6MWT work (W_6MWT) (i.e. the product of walked distance and body weight). However, these equations were not yet critically compared. Objective: To compare the equations to estimate Wmax based on the 6MWT proposed by Hill et al. and Luxton et al. in Brazilian patients with COPD. Methods: 49 patients with COPD (27 male; 65±7 years; FEV₁ 46±16%predicted) performed the CPET and the 6MWT. Estimation of Wmax was based on the equation proposed by Luxton et al. (L) and the two equations proposed by Hill et al., which take into account the distance covered in the 6MWT (H1) and the W_6MWT (H2). These three estimations were compared to the real Wmax achieved in the CPET. Results: Modest correlations were found between the real Wmax and the three equations (L: r=0.45; H1: r=0.40; H2: r=0.53; p<0.001 for all). However, the three equations showed significant overestimation when compared to real Wmax (L = 70±26watts; H1 = 55±18watts; H2 = 59±11watts versus real Wmax: 38±19watts; p<0.0001 when comparing all three estimations with real Wmax). Conclusion: The proposed equations provided estimations only modestly correlated with the real Wmax obtained in a CPET in patients with COPD, and overestimation by all three equations occurred. Either there is need for population-specific and/or more accurate equations, or the usefulness of such type of estimation should be questioned.

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C. A. Camillo, C. H. Nassu Higa, B. R. Kajimoto Dellarosa, D. N. Suzumura, I. Lopes de Brito, V. S. Probst, D. Ramos, V. Cavalheri, F. Pitta (Presidente Prudente, Londrina, Brazil). Analysis of different equations for estimation of maximal workload in patients with COPD. Eur Respir J 2010; 36: Suppl. 54, 4885

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