Source: Annual Congress 2010 - Influenza A (H1N1) and other viral infections: therapeutic aspects
Disease area: Respiratory critical care, Respiratory infections

Abstract

Background. The influenza virus A (H1N1) "swine flu" became a new menace to humanity in 2009.
Purpose of the study: to explore features of pneumonia caused by influenza during epidemic of swine-flu in Western Ukraine.
Materials and methods: We had analyzed 154 cases of CAP, which emerged as a complication of influenza and required hospitalization in an intensive care unit during epidemic of swine-flu in Ukraine. All the patients were conducted clinical examination: physical examination, clinical blood analysis, determination of body temperature and oxygen saturation, chest x-ray.
Results of the study: all the patients were hospitalized in critically condition, approximately on 4-7 days of onset. Severe pneumonias have been developed mostly in young people and pregnants. The obesity highly correlated with the severity course of the disease and ARDS development. The following clinical features were identified in majority of the patients: general weakness, muscle and joints / bones pains, increasing of body temperature to 38-39 degrees, non-productive or inefficient cough, the increasing of the breath rate, breathlessness, decreasing of oxygen saturation. Left shifted leukogram with 20-30% increasing of stab neutrophils was observed. Chest X-ray changes were manifested in a massive confluent shadow mostly in lower lobes of both lungs.Complications of CAP evolved with great speed and were manifested in: acute respiratory insufficiency, ARDS, pulmonary edema, infectious-toxic shock.
Conclusions: the disease strikes mainly young people. Fever and respiratory insufficiency symptoms were present in most of the patients first of all.

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Citations should be made in the following way:
M. Ostrovskyy, O. Varunkiv, I. Savelikhina (Ivano-Frankivsk, Ukraine). Regional features of pneumonia caused by influenza during epidemics of influenza virus A (H1N1) in western Ukraine. Eur Respir J 2010; 36: Suppl. 54, 2994

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