Source: Annual Congress 2010 - Acute respiratory failure
Disease area: Respiratory critical care

Abstract

Acute respiratory distress syndrome (ARDS) in patients after renal transplantation is significantly higher than the general population.
Thirty-one renal transplant patients with active pulmonary infection were hospitalized in the pulmonary department for a period of 18 months. To clarify the etiology of the infection were used different noninvasive and invasive diagnostic methods. Despite the ongoing complex treatment eight of the patients (25.8%) developed ARDS. Of the analysis it was found that the following factors are associated with the high risk of ARDS: 1) development of infection between first and sixth months after transplantation, 2) four of the patients (50%) with ARDS were with sepsis, 3) active Cytomegalovirus infection (7 patients, 87.5%). Factors such as duration of dialysis before transplantation and the type of immunosuppressive treatment provided no significant importance for ARDS. In three of the patients the treatment of ARDS were provided with noninvasive ventilation (NIV). The other five patients were intubated and treated with mechanical ventilation. The length of stay by survivors in the group with NIV treatment is mean 12 days vs 17 days in the group with mechanical ventilation. The four patients with ARDS died. They were in the mechanical ventilation group.
Early diagnosis and timely treatment of ARDS with non-invasive ventilation, the prevention of Cytomegalovirus infection could lead to a reduction in the development of ARDS and mortality in patients after renal transplantation.

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Citations should be made in the following way:
V. Pencheva, O. Georgiev, D. Petrova (Sofia, Bulgaria). Acute respiratory distress syndrome after renal transplantation. Eur Respir J 2010; 36: Suppl. 54, 2291

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