Source: Annual Congress 2010 - Nocturnal cardiology: chronic heart failure, acute chest syndrome, coronary artery disease and collagen vascular disease
Disease area: Sleep and breathing disorders

Abstract

The Obstructive Sleep Apnea/Hypopneia Syndrome (OSAHS) of increasing prevalence in recent years, is predominant in middle aged men (24% in males versus 9% in females), with an even higher prevalence in risk groups (50%).
Objective: to assess the prevalence of OSAHS in patients hospitalized for Acute Coronary Syndrome (ACS).
Material and Methods: a prospective randomized study, applying clinical protocol of investigation, for ACS and OSAHS. Selecting the 1st patient of the day (from 0 to 24 hours) admitted with ACS for the study of a possible OSAHS, with Cardiorespiratory sleep study (Stardust ® II), performed after stabilization, and confirmed later by Polysomnography (PSG) (Alice® 4), being held between 1 and 2 months after. Research was made after the patient‘s informed consent. Data processed with SPSS version 16.
Results: eighty-eight patients were included over a period of 1 year, October 2007 to November 2008, with 65 males (73.9%) and a mean age of 58 years (Max.75: Min.37). Population with mean BMI of 27.4 kg/m2 (Max.41, 7: Min.20, 6). Only 73 patients conclued the investigation protocol, that was compatible with the existence of OSAHS in 46 cases (63%), classifying it as severe in 21 (28,8%) cases (AHI> 30/h). The obesity and diastolic dysfunction predominant in OSAHS group, diferences statistically significant. It therapeutic CPAP, auto-ajusted CPAP or Pressure support servo-ventilation was established, according to the clinical situation, in 36 cases.
Conclusion: the high prevalence of OSAHS in this population, which the current study allowed to diagnose and treat, seems to make the point that it is justified to include the cardiorespiratory sleep study in investigation of ACS patients.

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Citations should be made in the following way:
B. Conde, T. Calvo, P. Fontes, A. Afonso, I. Moreira (Vila Real, Portugal). Acute coronary syndrome and OSAHS an unequivocal association (prospective study). Eur Respir J 2010; 36: Suppl. 54, 908

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