Source: Annual Congress 2010 - Novel insights into the pathophysiology of asthma and COPD
Disease area: Airway diseases



Rating:

Share or cite this content

Citations should be made in the following way:
J. Zhang, L. Wu, C. Bai, J. Qu, M. J. Merrilees, P. N. Black (Shanghai, Auckland, China; Auckland, New Zealand). The senescence and impaired elastic synthesis in pulmonary fibroblasts from subjects with COPD. Eur Respir J 2010; 36: Suppl. 54, 2472

Member's Comments

No comment yet.

Related content which might interest you: Remodelling in the bronchi of patients with COPD: defective ECM deposition and repair by pulmonary fibroblasts Source: Annual Congress 2013 –Immunopathology of COPD: contribution of advancements of new therapeutic agents Year: 2013 Lung fibroblasts from COPD patients presented a reduced response to TGF-β1 for proliferation and elastin synthesis Source: Annual Congress 2011 - Molecular: pathology of infectious and inflammatory lung disease Year: 2011 NOX4/NADPH oxidase expression is increased in pulmonary fibroblasts from patients with idiopathic pulmonary fibrosis and mediates TGFβ1-induced fibroblast differentiation into myofibroblasts Source: Annual Congress 2009 - From emphysema to fibrosis: mechanisms of cellular remodelling in the diseased lung Year: 2009 Small airway fibroblasts from COPD patients are senescent and pro-fibrotic Source: International Congress 2018 – New kids on the block: novel molecular pathways and therapeutic targets in chronic lung diseases Year: 2018 Altered phenotype of COPD primary fibroblasts from airway and alveolar tissues: proliferation and apoptosis. Source: International Congress 2019 – Research and innovation in airway diseases Year: 2019 Smoking induced pulmonary vascular remodelling in patients with mild COPD Source: Eur Respir J 2007; 30: Suppl. 51, 605s Year: 2007 Airway smooth muscle cells from patients with COPD exhibit a higher degree of cellular proliferation and steroid insensitivity than that from healthy patients Source: Annual Congress 2011 - Airway smooth muscle cells and fibroblasts: cell biology Year: 2011 Altered iron metabolism and elevated cellular senescence in COPD small airway epithelial cells Source: Virtual Congress 2020 – Metabolic alterations and ageing in lung disease Year: 2020 IL-17A is elevated in patients with COPD and contributes to airway remodeling by acting on fibroblasts Source: International Congress 2016 – What's new in biomarker analysis? Year: 2016 Nintedanib inhibits contractile activity of lung myofibroblasts in a cellular model of scleroderma associated pulmonary fibrosis Source: International Congress 2018 – CTD-ILD and hypersensitivity pneumonitis: from the bench to the bedside Year: 2018 COPD patients exhibit abnormally increased peripheral neutrophil stiffening not different from smokers with normal lung function Source: Annual Congress 2009 - Functional insights into COPD Year: 2009 Arterial remodelling in patients with idiopathic pulmonary fibrosis (IPF) and the possible role of endothelial to mesenchymal transition (EndMT) Source: Virtual Congress 2021 – Mechanistic pathways in chronic and new lung diseases Year: 2021 Increased lung apoptosis and expression of ceramide in subjects with chronic obstructive pulmonary disease (COPD) Source: Annual Congress 2009 - COPD: basic science and clinical studies Year: 2009 Potential contribution of precursor cells to vascular remodeling in the AdTGF-β1 model of lung fibrosis and pulmonary hypertension Source: Annual Congress 2011 - Experimental pulmonary hypertension Year: 2011 The increased contractility of idiopathic pulmonary fibrosis lung fibroblasts is dependent on angiotensin signalling Source: Annual Congress 2010 - Pathogenesis of diffuse parenchymal lung disease Year: 2010 MicroRNA-34a drives small airway fibroblast cellular senescence in COPD Source: International Congress 2017 – New Mechanistic Findings in COPD Year: 2017 Are asthma and COPD translation control diseases? Translational defect of cell cycle regulators C/EBP-α and -δ in airway smooth muscle cells (ASMC) of patients with asthma and COPD Source: Eur Respir J 2005; 26: Suppl. 49, 20s Year: 2005 Characterization of the cellular and extracellular changes in remodeled arteries of smokers and patients with chronic obstructive pulmonary disease Source: Eur Respir J 2001; 18: Suppl. 33, 491s Year: 2001 Collagen V nasal tolerance reverts pulmonary immune cells proliferation and interstitium remodeling in experimental scleroderma Source: Annual Congress 2007 - Miscellaneous interstitial lung diseases related to systemic and other diseases Year: 2007