Source: Annual Congress 2010 - Nocturnal cardiology: chronic heart failure, acute chest syndrome, coronary artery disease and collagen vascular disease
Disease area: Pulmonary vascular diseases, Sleep and breathing disorders

Abstract

Objective: to study the cardiac ECHO indices in groups of patients with isolated obstructive sleep apnea syndrome (OSA), and overlap syndrome (OS) – OSA in combination with COPD. Patients and methods: we observed 63 patients, 31 with isolated OSA, and 32 with OS. All patients were provided cardiac ECHO (Medison ²Sono Ace² 9900), overnight polysomnography with pulse oximetry (²SleepLab², Erich Jager), bodyplethysmography (²MasterLab², Erich Jager) and Epworth Sleepiness Scale. Mean age of patients was 56,0 ±1,7 in group of isolated OSA(I), and 60,7 ± 1,6 in group of OS (II). Mean respiratory disturbance index was 34,1 ± 3,9 per hour (I), and 21,8 ± 1,9 per hour (II). Mean FEV1 was 100,3 ± 3,0 % in I group, and 62,0 ± 3,2 % in II group. Mean FEV1/FVC was 78,6 ± 1,2 in I group, and 56,4 ± 2,0 in II group. Results: Left ventricle mass was 186,95 ± 7,82 g (I) and 213,36 ± 9,52 g (II). Interventricular septal thickness and left ventricular thickness were 10,14 ± 0,03 mm. and 10,09 ± 0,03 mm. in I group, and 10,17 ± 0,03 mm. and 10,1 ± 0,03 mm. in II group. Ejection fraction was 63,78 % ± 0,48 and 61,09 % ± 1,31 in I and II groups respectively. Pulmonary arthery systolic pressure was 20,74 ± 1,19 mmHg and 27,27 ± 2,17 mmHg in I and II groups respectively. Left ventricle mass and pulmonary arthery systolic pressure were significantly higher (p=0,02 and 0,03 respectively) in II group of patients. Conclusion: In patients with OS left ventricle mass and pulmonary arthery systolic pressure were significantly higher then normal and in group of OSA patients.

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Citations should be made in the following way:
K. Miheieva, U. Sirenko, S. Palkovskii, I. Djavad (Kiev, Ukraine). Heart structure in patients with obstructive sleep apnea and COPD. Eur Respir J 2010; 36: Suppl. 54, 905

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