Activation of beta2-adrenoceptor signaling is required for IL-13 induced production of mucous metaplasia

R. A. Bond, O. Omuluabi, L. Nguyen, B. J. Knoll (Houston, United States Of America)

Source: Annual Congress 2010 - Regulation of airway pharmacology
Session: Regulation of airway pharmacology
Session type: Thematic Poster Session
Number: 1243
Disease area: Airway diseases

Congress or journal article abstract

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
R. A. Bond, O. Omuluabi, L. Nguyen, B. J. Knoll (Houston, United States Of America). Activation of beta2-adrenoceptor signaling is required for IL-13 induced production of mucous metaplasia. Eur Respir J 2010; 36: Suppl. 54, 1243

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Attenuated cytokine response and enhanced toll-like receptor expression by budesonide in bronchial epithelial cells
Source: Eur Respir J 2006; 28: Suppl. 50, 101s
Year: 2006

TLR4 signaling potentiates airway secretion from the swine submucosal gland via NO/cGMP/cGK pathway
Source: Annual Congress 2012 - Cellular signalling mechanisms in the airways
Year: 2012

Inhibition of ER stress suppresses IL-13 induced airway epithelial remodeling
Source: International Congress 2019 – COPD, asthma and rhinitis: from cellular mechanisms to patients’ clinical responses
Year: 2019

IL-4 modulation of rhinovirus-induced CCL20/MIP-3a production in bronchial epithelial cells
Source: Annual Congress 2009 - Viruses and respiratory infections: prevalence and mechanisms of infection
Year: 2009


NOTCH-1 activation sustains hyperexpression of IL-33 in the epithelium of nasal polyps
Source: International Congress 2017 – Systemic and airway biomarkers
Year: 2017

TLR4 signaling as a potentiator in the airway submucosal gland secretion
Source: Annual Congress 2010 - Lung cell biology and immunology
Year: 2010

Effects of budesonide on p38 MAPK activation, apoptosis and IL-8 secretion, induced by TNF-alpha and Haemophilus influenzae in human bronchial epithelial cells
Source: Annual Congress 2010 - Regulation of airway pharmacology
Year: 2010

Rhinovirus-induced proinflammatory cascade in bronchial epithelial cells requires xanthine-oxidase system activation
Source: Annual Congress 2008 - New diagnostic methods in viral and atypical infections
Year: 2008


IL-8 and TSLP production as markers of bronchial epithelial cell activation in IL-17A mediated airway inflammation in COPD: Role of tiotropium
Source: Annual Congress 2013 –New insights into epigenetic mechanisms in the lung
Year: 2013

TGFβ overproduction in asthma reduces the epithelial repair by down-regulating the leptin/leptin receptor pathway
Source: Eur Respir J 2007; 30: Suppl. 51, 59s
Year: 2007

Toll-like receptor stimulation induces airway hyperresponsiveness to bradykinin, an effect mediated by JNK and NF-κB signaling pathways
Source: Eur Respir J 2005; 26: Suppl. 49, 732s
Year: 2005

Protease activated receptor 2 (PAR2) antagonism reduces pro-inflammatory cytokine production in bronchial epithelial cells
Source: Virtual Congress 2020 – Novel immunopathological mechanisms of lung disease: knowledge from translational studies
Year: 2020


CD40 ligation modulates inflammatory cytokines production by human bronchial epithelial cells
Source: Eur Respir J 2001; 18: Suppl. 33, 246s
Year: 2001

Activation of PAR-2 enhances ICAM-1 expression and IL-8 release in airway epithelial cells
Source: Eur Respir J 2002; 20: Suppl. 38, 571s
Year: 2002

TLR4 mediates LPS-induced mucus hypersecretion in rat airway
Source: Annual Congress 2007 - Epithelial networks in the airways
Year: 2007


Role of IL-13Ra2 in modulating IL-13 induced MUC5AC and ciliary changes in healthy and CRSwNP mucosa
Source: International Congress 2019 – Novel insights from in vitro and in vivo models of lung disease
Year: 2019

Interleukin-17A activation on bronchial epithelium and basophils: a novel inflammatory mechanism
Source: Eur Respir J 2010; 35: 883-893
Year: 2010



The muscarinic receptors promote IL-8 release in airway epithelial cells via the pERK42/44 and NF-kB pathways
Source: Eur Respir J 2006; 28: Suppl. 50, 746s
Year: 2006

Intranasal steroids decrease eosinophils but not mucin expression in nasal polyps
Source: Eur Respir J 2004; 24 : 594-600
Year: 2004



dsRNA enhances eotaxin-3 production through interleukin-4 receptor upregulation in airway epithelial cells
Source: Eur Respir J 2005; 26: 795-803
Year: 2005