Source: Annual Congress 2010 - Occupational asthma
Disease area: Airway diseases

Abstract

Background and Aims Hairdressers are exposed to irritating and sensitising agents and often complain of increasing airway symptoms during work periods. The aims were to compare symptoms, inflammatory markers in nasal lavage (NAL), and quality of life (QOL) during a month of work after holidays in hairdressers with bleaching powder related nasal spts (S+; n=17) compared to hairdressers without symptoms (S-; n=19) and hayfever patients (HP; n=10) during the first month of the pollen season.
Methods All groups completed a diary regarding nasal symptoms (blockage, secretion, itching and sneezing), and exposure to hairdresser chemicals (S groups). Before, after one and four weeks of exposure NAL was sampled for eosinifilic cationic protein (ECP) analysis. Questionnaires of QOL were completed before and after four weeks.
Results S+ increased in nasal symptoms during the study period. The other groups did not, but the HP group had more symptoms from the start. ECP increased in the S+ and HP groups [S 3.8 to 7.0; P=0.05, and HP 8.4 to 28.0; NS (medians, µg/L)]. There were no significant differences regarding exposure except for hair spray (0.569; P=0. 001) between the hairdresser groups. QOL weakened to the same extent in the S+ and the HP groups, whereas the S- group improved.
Conclusions Symptoms and inflammatory markers increased in the S+ group. With respect to capability of work and QOL, a month of work had the same effect on S+ as did a month‘s exposure to pollen on HP. No such effects were found among S-.

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Citations should be made in the following way:
K. Kronholm Diab, A. Axmon, J. Nielsen (Lund, Sweden). Nasal symptoms, inflammatory markers and quality of life during a work period in female hairdressers. Eur Respir J 2010; 36: Suppl. 54, 1464

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