Source: Annual Congress 2005 - Skeletal muscles: current concepts
Disease area: Airway diseases, Respiratory critical care

Abstract

Since inspiratory muscle fatigue (IMF) may cause an increase in breathing frequency (f_B) and/or a decrease in tidal volume (V_T), we aimed to distinguish the effects of diaphragm (DIA-F) and rib cage muscle (RCM-F) fatigue on breathing pattern and respiratory mechanics during an intensive endurance exercise. 10 healthy subjects performed a constant-load cycling test at 85% of maximal power to exhaustion with prior IMF and a cycling test of similar intensity and duration without prior IMF. IMF was induced by resistive breathing and assessed by measurement of oesophageal and gastric twitch pressures (-20%) during cervical magnetic stimulation. DIA-F increased V_T (+0.24±0.24 vs. -0.14±0.28 l, p=0.080), diaphragm pressure swings (+7.7±7.0 vs. -2.5±5.0 cmH₂O, p=0.049) and end-expiratory oesophageal pressure (+4.5±1.8 vs. +1.4±2.2 cmH₂O, p=0.048) to a greater extent than RCM-F. Both DIA-F and RCM-F can induce a >10% increase in minute ventilation with a higher f_B (5 out of 10 subjects), and increased RCM (+19±24%; p=0.041) and abdominal muscle (+31±37%; p=0.020) force production. These results indicate that RCM-F and not DIA-F is responsible for rapid shallow breathing during exercise, while tachypnea and increased minute ventilation with IMF do not depend on the type of fatigue. The larger decrease in end-expiratory lung volume with DIA-F vs. RCM-F may optimize the operating length of the fatigued diaphragm in order to preserve its function.
Supports: Swiss National Science Foundation (31-61941.00); AGIRàdom, France

Rating:

Share or cite this content

Citations should be made in the following way:
S. Verges, D. A. Notter, C. M. Spengler (Zurich, Switzerland). Influence of diaphragm and rib cage muscle fatigue on breathing during endurance exercise. Eur Respir J 2005; 26: Suppl. 49, 1670

Member's Comments

No comment yet.

Related content which might interest you: Effects of prior self-control exertion on inspiratory muscle endurance, fatigue and dyspnoea Source: International Congress 2019 – Lung function and respiratory muscle testing Year: 2019 Effects of Inspiratory muscle training on respiratory muscle strength, physical fitness and dyspnea in obese women. Source: International Congress 2019 – Assessment and training of respiratory muscles Year: 2019 Respiratory muscle endurance training increases fatigue-resistance of expiratory muscles during exercise Source: Eur Respir J 2001; 18: Suppl. 33, 177s Year: 2001 Expiratory muscle fatigue exacerbates exercise-induced locomotor muscle fatigue and impairs exercise performance Source: Annual Congress 2007 - Pathophysiology of respiratory muscles Year: 2007 Diaphragm and quadriceps muscle fatigue in self-paced cycling exercise of different durations Source: Annual Congress 2011 - Respiratory and skeletal muscle assessment in health and disease Year: 2011 The effects of inspiratory muscles loading on core endurance Source: International Congress 2016 – Postural balance, respiratory muscles, and comorbidities in chronic respiratory disease Year: 2016 Voluntary phasic activation-relaxation of expiratory muscles improves exercise endurance in patients with diaphragm dysfunction Source: Eur Respir J 2004; 24: Suppl. 48, 242s Year: 2004 The respiratory muscles during exercise Source: Breathe 2016; 12: 165-168 Year: 2016 The effects of inspiratory muscle training on breathing mechanics during fixed load cycling exercise Source: Annual Congress 2011 - Respiratory and skeletal muscle assessment in health and disease Year: 2011 Perception of leg fatigue and contractile fatigue of quadriceps during exercise in COPD Source: Eur Respir J 2004; 24: Suppl. 48, 217s Year: 2004 Effects of maximal volitional hyperpnoea on exercise tolerance and locomotor muscle fatigue Source: International Congress 2018 – Mechanisms that underlie exercise limitation in various respiratory diseases Year: 2018 Fatiguing inspiratory muscle work accelerates limb muscle fatigue Source: Eur Respir J 2005; 26: Suppl. 49, 571s Year: 2005 Non-invasive assessment of ribcage inspiratory muscle fatigue during two endurance tests in healthy subjects Source: Virtual Congress 2020 – From respiratory physiology to clinical practice: exercise and respiratory muscles Year: 2020 Effect of pulmonary rehabilitation on quadriceps fatigability during exercise training Source: Annual Congress 2008 - Rehabilitation and influencing factors Year: 2008 Effect of ageing on respiratory muscle endurance Source: Eur Respir J 2002; 20: Suppl. 38, 498s Year: 2002 Isometric limb muscle endurance in normal and COPD Source: Eur Respir J 2001; 18: Suppl. 33, 83s Year: 2001 Diaphragm fatigue during incremental muscle training Source: Annual Congress 2010 - Respiratory muscles and breathing: assessment and training Year: 2010 No effect of low-intensity endurance exercise on muscle necrosis in the diaphragm of mdx mice Source: International Congress 2014 – Pathophysiological mechanisms at different scales Year: 2014 Cycling with fatigued respiratory muscles increases leg muscle fatigue Source: Eur Respir J 2003; 22: Suppl. 45, 573s Year: 2003 Influence of whole body exercise duration on diaphragmatic central fatigue Source: Eur Respir J 2005; 26: Suppl. 49, 573s Year: 2005