Platelets induce airway smooth muscle cell proliferation through mechanisms dependent on ROS and 5-LOX metabolites

A. C. B. Svensson, T. Bengtsson, M. Grenegård, E. G. Lindström (Linköping, Sweden)

Source: Annual Congress 2005 - Pulmonary hypertension and fibrosis: novel mechanisms
Session: Pulmonary hypertension and fibrosis: novel mechanisms
Session type: Oral Presentation
Number: 1625
Disease area: Airway diseases

Congress or journal article abstractSlide presentation

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
A. C. B. Svensson, T. Bengtsson, M. Grenegård, E. G. Lindström (Linköping, Sweden). Platelets induce airway smooth muscle cell proliferation through mechanisms dependent on ROS and 5-LOX metabolites. Eur Respir J 2005; 26: Suppl. 49, 1625

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Responses of bronchial smooth muscle to inflammation and disease
Source: Annual Congress 2005 - Role of the bronchial smooth muscle in regulating airway disease
Year: 2005

TGFβ1-induced extracellular matrix production enhances airway smooth muscle cell proliferation
Source: Annual Congress 2011 - Airway smooth muscle cells and fibroblasts: cell biology
Year: 2011


NGF signalling pathways in human airway smooth muscle proliferation
Source: Eur Respir J 2005; 26: Suppl. 49, 579s
Year: 2005

Protein kinase C and MAPK pathways transcriptionally regulate eotaxin release from human airway smooth muscle cells (HASMC)
Source: Annual Congress 2005 - Inflammation and the airway smooth muscle: cellular and pharmacological interactions
Year: 2005


Extracellular matrix regulates human airway smooth muscle cell migration
Source: Eur Respir J 2004; 24 : 545-551
Year: 2004



Remicade suppresses cytokine-induced up-regulation of bradykinin receptor-mediated airway smooth muscle contractions
Source: Annual Congress 2005 - Inflammation and the airway smooth muscle: cellular and pharmacological interactions
Year: 2005


Upregulation of airway smooth muscle (ASM) cell apoptosis may limit ASM growth during airway remodeling in experimental asthma
Source: Annual Congress 2008 - Novel mechanisms in the pathogenesis of pulmonary inflammation
Year: 2008

Increased secretion of leukaemia inhibitory factor by immature airway smooth muscle cells enhances intracellular signalling and airway contractility
Source: Eur Respir J 2006; 28: Suppl. 50, 260s
Year: 2006

Fractalkine-induced smooth muscle cell proliferation in pulmonary hypertension
Source: Eur Respir J 2007; 29: 937-943
Year: 2007



Azithromycin has an antiproliferative and autophagic effect on airway smooth muscle cells
Source: Eur Respir J 2009; 34: 721
Year: 2009



Rho is involved in the inhibitory effects of simvastatin on proliferation of human airway smooth muscle cells
Source: Eur Respir J 2005; 26: Suppl. 49, 223s
Year: 2005

Mir-17 modulates smooth muscle cell markers, apoptosis and BMPR-II levels in human pulmonary artery smooth muscle cells
Source: Annual Congress 2012 - Pulmonary circulation: basic mechanisms, animal models and experimental treatments
Year: 2012

Mitogenic effects of RBL-1 cell mediators on human airway smooth muscle (ASM) cells are via nonproteolitic actions
Source: Eur Respir J 2003; 22: Suppl. 45, 81s
Year: 2003

Regulation of human airway smooth muscle migration and matrix production by PPAR-ligands
Source: Eur Respir J 2006; 28: Suppl. 50, 856s
Year: 2006

MNK-1 inhibition reduces proliferation and CXCL10 in airway smooth muscle cells
Source: Annual Congress 2013 –Airway smooth muscle and cell biology
Year: 2013

Eosinophils promote airway smooth muscle cells differentiation to the contractile phenotype in asthma
Source: International Congress 2019 – Novel mechanisms elucidated by translational studies of asthma
Year: 2019

Caveolin-1 in force regulation following airway smooth muscle inflammation
Source: Annual Congress 2008 - Respiratory muscles in disease
Year: 2008


Plasminogen-stimulated inflammatory cytokine production by airway smooth muscle cells is regulated by annexin A2
Source: Annual Congress 2013 –Airway smooth muscle and cell biology
Year: 2013

Contribution of bronchial smooth muscle to inflammation
Source: Annual Congress 2005 - Role of the bronchial smooth muscle in regulating airway disease
Year: 2005

Eotaxin/CCL11 inhibits proliferation of human airway smooth muscle cells
Source: Eur Respir J 2005; 26: Suppl. 49, 127s
Year: 2005