The cytoplasmic tail of IL-13Rα2 regulates both IL-4 and IL-13 signal transduction Source: Eur Respir J 2006; 28: Suppl. 50, 338s Year: 2006
Increased activation of TGF beta signal transduction via Smad2/3 in the airways of mice lacking T-bet Source: Eur Respir J 2002; 20: Suppl. 38, 1s Year: 2002
Cytokine modulators as novel therapies for airway disease Source: Eur Respir J 2001; 18: 67S-77S Year: 2001
Polymorphisms of the IL-4 and IL-4 receptor alpha chain genes and bronchial asthma Source: Eur Respir J 2005; 26: Suppl. 49, 708s Year: 2005
NF-AT and GATA3 complex mediates anti-CD3/CD28-induced IL-13 expression: effect of glucocorticoid Source: Annual Congress 2008 - Novel therapeutic approaches and immunological mechanisms in airway cell pathobiology Year: 2008
Lung expression of interleukin-13 (IL-13) and interferon gamma (IFNg) in emphysema in human Source: Eur Respir J 2002; 20: Suppl. 38, 584s Year: 2002
dsRNA enhances eotaxin-3 production through interleukin-4 receptor upregulation in airway epithelial cells Source: Eur Respir J 2005; 26: 795-803 Year: 2005
Interferon gamma decreases interleukin-8 production and neurokinin-1 receptor expression in lung alveolar epithelial cells Source: Eur Respir J 2001; 18: Suppl. 33, 80s Year: 2001
T-helper cell type-1 transcription factor T-bet is upregulated in pulmonary sarcoidosis Source: Eur Respir J 2011; 38: 1136-1144 Year: 2011
Il-4 and IL-13 act independently and synergistically to drive type 2 inflammation Source: International Congress 2019 – Novel mechanisms elucidated by translational studies of asthma Year: 2019
Transforming growth factor beta (TGF-ß) pathway activation by IPF fibroblast-derived soluble factors is mediated by IL-6 trans-signaling Source: Virtual Congress 2020 – Translational therapeutic advances Year: 2020
IL-33 augments rhinovirus-induced type 2 immune responses in asthma via selective upregulation of one chain of the IL-33 receptor. Source: International Congress 2017 – "Alarming" immunological patterns in asthma Year: 2017
Increased phospholylated Smad 2 in human eosinophils stimulated by IL-5 Source: Eur Respir J 2004; 24: Suppl. 48, 37s Year: 2004
Upregulation of interleukin 13 receptor alpha 2 (IL-13RA2) expression in idiopathic pulmonary fibrosis Source: Eur Respir J 2005; 26: Suppl. 49, 267s Year: 2005
Interleukin (IL-13) modulates allergen-induced airway hyperresponsiveness by a pathway independent of IL-5 or eotaxin in mice Source: Eur Respir J 2003; 22: Suppl. 45, 194s Year: 2003
Late-breaking abstract: Activation of the macrophage inflammasome by TLR3 ligation potentiates release of IL-8 and IP-10 from alveolar type II epithelial cells via a paracrine cytokine network Source: Annual Congress 2011 - Epithelial cells: role in health and disease Year: 2011
The expression of IL17RA (the common subunit of IL-17A and IL-25 receptor) on sputum macrophages in asthma patients Source: Virtual Congress 2021 – Pearls in immunology, outcome studies and clinical trials in asthma, alpha-1 antitrypsin deficiency and COPD Year: 2021
IL-4 induces Th2 cells to resist the IL-27 counterregulation by downregulating STAT1 and STAT2 phosphorylation Source: Annual Congress 2012 - Asthma: mechanisms of airway inflammation Year: 2012
Interferon-gamma downregulates the major group rhinovirus receptor intercellular adhesion molecule 1 via a signal transducer and activator of transcription-1-dependent mechanisms Source: Eur Respir J 2001; 18: Suppl. 33, 475s Year: 2001
IL33 receptor activation is IL33 isoform and receptor genotype specific Source: International Congress 2019 – Crosstalk in chronic pulmonary diseases Year: 2019