Cigarette smoke causes increased susceptibility to respiratory pathogens: role for innate immunity toll-like receptor (TLR4) inactivation

S. Bozinovski, R. Vlahos, G. P. Anderson (Parkville, Australia)

Source: Annual Congress 2006 - Airway cell biology
Session: Airway cell biology
Session type: Poster Discussion
Number: 4917
Disease area: Airway diseases

Congress or journal article abstract

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
S. Bozinovski, R. Vlahos, G. P. Anderson (Parkville, Australia). Cigarette smoke causes increased susceptibility to respiratory pathogens: role for innate immunity toll-like receptor (TLR4) inactivation. Eur Respir J 2006; 28: Suppl. 50, 4917

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Innate immune response of the lung to bacterial and viral stimuli: evidence for a role of epithelial toll-like receptor (TLR) 4 and TLR3
Source: Eur Respir J 2004; 24: Suppl. 48, 210s
Year: 2004

Cigarette smoke up-regulates toll like receptor 4 (TLR4) expression and enhances TLR4 mediated responses
Source: Eur Respir J 2005; 26: Suppl. 49, 555s
Year: 2005

Toll-like receptor 7 function is reduced in adolescents with asthma
Source: Eur Respir J 2010; 35: 64-71
Year: 2010



Microbiota educates innate immune response to Toll-like receptors stimulation and RSV infection in lung
Source: International Congress 2019 – The microbiome: novel data across respiratory diseases
Year: 2019




Activation of eosinophils via toll-like receptor (TLR)3, TLR7 and TLR9: link between viral infection and asthma?
Source: Annual Congress 2007 - Novel aspects in airway inflammation in human asthma and rhinitis
Year: 2007



Host defence during Klebsiella pneumonia relies on haematopoietic-expressed Toll-like receptors 4 and 2
Source: Eur Respir J 2011; 37: 848-857
Year: 2011



Cigarette smoke induces CXCL8 production by human neutrophils via activation of TLR9 receptor
Source: Eur Respir J 2010; 36: 1143-1154
Year: 2010



Oral presentation: Inhibition of innate host defense in airway epithelial cells by cigarette smoke in an in vitro infection model caused by suppression of NF-kB activation
Source: Lung Science Conference 2010 - Biology of gene-environment interactions in the lung
Year: 2010

Cigarette smoking augments toll-like receptor 3 expression and responses in macrophages
Source: Annual Congress 2011 - Macrophages and neutrophils in chronic lung disease
Year: 2011

LSC 2010 Abstract: Inhibition of innate host defense in airway epithelial cells by cigarette smoke in an in vitro infection model caused by suppression of NF-κB activation
Source: Annual Congress 2010 - Epithelial cells: cell biology and role in lung disease
Year: 2010

Influence of Toll-like receptor 4 (TLR4) on cellular signaling of acute lung injury
Source: Eur Respir J 2003; 22: Suppl. 45, 268s
Year: 2003

Genetic aspects of susceptibility to air pollution
Source: Eur Respir J 2003; 21: 52S-56S
Year: 2003



Activation of eosinophils via Toll-like receptor (TLR)3, TLR7 and TLR9: link between viral infection and asthma?
Source: Eur Respir Rev 2008; 17: 46-48
Year: 2008



Impaired expression of Toll-like receptor 2 in nontuberculous mycobacterial lung disease
Source: Eur Respir J 2007; 30: 736-742
Year: 2007



Role of Toll-like receptor 4 in acute pulmonary inflammation induced by bacterial components in mice
Source: Eur Respir J 2005; 26: Suppl. 49, 730s
Year: 2005

Human rhinovirus impairs macrophage innate immune responses to bacteria via the interferon pathway in COPD
Source: International Congress 2018 – The airway microbiome across the spectrum of airway disease
Year: 2018



Antiapoptotic and proinflammatory function of toll-like receptor 2 in acute C. pneumoniae infection of COPD lung tissue
Source: Eur Respir J 2006; 28: Suppl. 50, 575s
Year: 2006

Chlamydia pneumoniae persists in COPD lung tissue: predominant role of toll-like receptor 2 versus 4 in chlamydia pneumoniae-induced activation of pulmonary immune cells
Source: Eur Respir J 2004; 24: Suppl. 48, 240s
Year: 2004

Rare TLR2 mutations reduce TLR2 receptor function and can increase atopy risk
Source: Annual Congress 2008 - Risk factors for allergic asthma and allergic rhinitis
Year: 2008