The feasibility of neutrophil elastase inhibitor in the treatment of acute lung injury of post pneumonectomy patients

D. H. Kim, J. J. Hwang, K. D. Kim, J. W. Lee (Daejeon, Republic Of Korea)

Source: Annual Congress 2010 - Acute respiratory failure
Session: Acute respiratory failure
Session type: Thematic Poster Session
Number: 2283
Disease area: Respiratory critical care

Congress or journal article abstract

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
D. H. Kim, J. J. Hwang, K. D. Kim, J. W. Lee (Daejeon, Republic Of Korea). The feasibility of neutrophil elastase inhibitor in the treatment of acute lung injury of post pneumonectomy patients. Eur Respir J 2010; 36: Suppl. 54, 2283

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Effect of sivelestat in patients with acute lung injury
Source: Eur Respir J 2006; 28: Suppl. 50, 347s
Year: 2006

Usefulness of selective neutrophil elastase inhibitor, sivelestat, in ALI patients with SIRS
Source: Annual Congress 2012 - How to use technology to provide better critical care
Year: 2012



Addition of neutrophil elastase inhibitor to flushing solution decreases reperfusion injury in rat lung transplantation
Source: Eur Respir J 2005; 26: Suppl. 49, 176s
Year: 2005

Gabexate mesilate attenuates ischemia-reperfusion injury of lung grafts via the inhibition of neutrophil activation
Source: Annual Congress 2005 - Recent advances in graft dysfunction after lung transplantation
Year: 2005


Effects of a neutrophil elastase inhibitor against mediators of acute exacerbation of pulmonary fibrosis: a new therapeutic strategy
Source: Annual Congress 2008 - New therapeutic strategies in idiopathic pulmonary fibrosis
Year: 2008

The effect of mercaptoethylguanidine on acute lung injury associated with sepsis
Source: Eur Respir J 2003; 22: Suppl. 45, 451s
Year: 2003

Perioperative alveolar epithelial damage is a determinant of early acute lung injury (ALI) following oesophagectomy
Source: Annual Congress 2010 - Novel markers of lung injury
Year: 2010

Predictive role of neutrophil elastase in the follow-up of patients with interstitial lung diseases
Source: Eur Respir J 2001; 18: Suppl. 33, 409s
Year: 2001

Early short-term versus prolonged low-dose methylprednisolone therapy in acute lung injury
Source: Eur Respir J 2009; 33: 634-645
Year: 2009



A novel approach for optimal lung recruitment in acute lung injury
Source: Annual Congress 2005 - Pulmonary function outcome, respiratory morbidity in prematurely born children and acute lung injury
Year: 2005


Usefulness of a selective neutrophil elastase inhibitor and a recombinant human soluble thrombomodulin in patients with ARDS and DIC
Source: Annual Congress 2013 –Acute respiratory failure, ARDS and severe COPD exacerbations
Year: 2013


Pioglitazone attenuates endotoxin-induced acute lung injury by reducing neutrophil recruitment
Source: Eur Respir J 2012; 40: 416-423
Year: 2012



The association between LASSBio596 and surfactant improves lung morpho-function and reduces the inflammatory process in experimental sepsis-induced acute lung injury
Source: Annual Congress 2010 - Acute respiratory failure
Year: 2010

Effects of phosphodiesterase inhibitors on the lung functions in a saline lavage-induced model of acute lung injury
Source: International Congress 2017 – Towards new anti-inflammatory and anti-fibrotic agents
Year: 2017



Effect of curcumin on LPS-induced neutrophil activation and acute lung injury
Source: Annual Congress 2012 - Lung injury, respiratory muscles and mechanical ventilation
Year: 2012

Prophylactic neutrophil elastase inhibitor (sivelestat) attenuates subsequent ventilator-induced lung injury
Source: International Congress 2014 – ARDS, skeletal muscles, physiology and weaning
Year: 2014

CXCL5-dependent neutrophil recruitment harms lung barrier function in acute lung injury
Source: International Congress 2018 – Triggers of acute lung injury: mechanical ventilation and oxygen levels
Year: 2018

Inhibition of neutrophil elastase contributes to attenuationof lipopolysaccharide-induced acute lung injuryduring neutropenia recovery in mice
Source: International Congress 2017 – Anti-inflammatory and pro-repair mediators in acute lung injury
Year: 2017

Neutrophil elastase inhibitor sivelestat ameliorates gefitinib, naphthalene-induced acute pneumonitis in mice
Source: International Congress 2015 – Novel insights into the pathobiology of acute lung injury
Year: 2015


Decreased levels of elafin in the lungs of patients with acute lung injury as a result of proteolytic cleavage by the proteasome
Source: Annual Congress 2012 - Mechanistic studies in airway cell biology
Year: 2012