Oral presentation: SOD3 protects cigarette smoke-induced emphysema associated with reduction of extracellular matrix fragmentation in mice

H. Yao, G. Arunachalam, S. Chung, J. Hwang, I. Sundar, V. Kinnula, J. Crapo, I. Rahman (Denver, Denver)

Source: Lung Science Conference 2010 - Biology of gene-environment interactions in the lung
Number: 13
Disease area: Airway diseases

PDF journal article, handout or slides

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
H. Yao, G. Arunachalam, S. Chung, J. Hwang, I. Sundar, V. Kinnula, J. Crapo, I. Rahman (Denver, Denver). Oral presentation: SOD3 protects cigarette smoke-induced emphysema associated with reduction of extracellular matrix fragmentation in mice. Lung Science Conference 2010 - Biology of gene-environment interactions in the lung

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Deficiency in neutrophil serine proteases protects mice from the development of cigarette smoke-induced emphysema
Source: Annual Congress 2010 - Proteases and the matrix
Year: 2010

Ablation of ADAM17 protects against cigarette smoke-induced emphysema in mice
Source: International Congress 2019 – Effects of environmental exposures in lung pathology and the underlying mechanisms
Year: 2019

Caspase-7 knockout mice are not protected against cigarette smoke-induced inflammation
Source: Annual Congress 2010 - Novel mechanisms in COPD
Year: 2010


Disruption of pulmonary lipid homeostasis drives cigarette smoke-induced lung inflammation in mice
Source: Eur Respir J 2015; 46: 1451-1460
Year: 2015



LSC Abstract – Cigarette smoke exposure accelerates airway mucus accumulation and inflammation in ENaC-overexpressed mice
Source: International Congress 2015 – Immunomodulation: basic science and clinical aspects
Year: 2015

Cigarette smoke results in accelerated airspace enlargement in Smad3 KO mice through increased alveolar cell apoptosis
Source: Annual Congress 2010 - Emerging mechanisms in lung injury
Year: 2010

Transgenic expression of human glutathione peroxidase-1 prevents cigarette smoke-induced inflammation and emphysema formation in mice
Source: Eur Respir J 2007; 30: Suppl. 51, 133s
Year: 2007

Simvastatin attenuates cigarette smoke extract induced extracellular matrix
Source: Annual Congress 2011 - COPD: clinical studies and animal cell models
Year: 2011

Acute cigarette smoke exposure in mice promotes airway inflammation consistent with the hallmarks of COPD
Source: Eur Respir J 2003; 22: Suppl. 45, 80s
Year: 2003

Attenuation of lung inflammation and emphysema induced by cigarette smoke exposure in CXCR3 knockout mice
Source: Annual Congress 2008 - Cell biology of asthma and COPD
Year: 2008


Oral presentation: Role of neutrophil serine proteases in the pathogenesis of cigarette smoke-induced emphysema
Source: Lung Science Conference 2010 - Biology of gene-environment interactions in the lung
Year: 2010

RAGE and cigarette smoke-induced pulmonary lesions: a chronic study on genetically manipulated mice
Source: Annual Congress 2009 - From emphysema to fibrosis: mechanisms of cellular remodelling in the diseased lung
Year: 2009

Mitochondria-targeted H2S suppresses and reverses cigarette smoke-induced inflammasome activity and lung injury in experimental COPD
Source: ERS Lung Science Conference 2020
Year: 2020

A neutrophil elastase inhibitor reduces cigarette smoke-induced remodelling of lung vessels
Source: Eur Respir J 2003; 22: 77-81
Year: 2003



Irisin secreted from muscle by exercise ameliorates emphysema of cigarette smoke-induced COPD in mice.
Source: International Congress 2019 – New molecular signatures in COPD, lung cancer and a1-antitrypsin deficiency
Year: 2019


LPS accelerates cigarette smoke-induced deterioration in respiratory function and airway inflammation in mice
Source: Annual Congress 2007 - New treatments for asthma and COPD - experimental evidence
Year: 2007


PDE4 inhibition prevents corticosteroid-resistant lung inflammation induced by cigarette smoke exposure in mice
Source: Annual Congress 2009 - Highlighting the epithelial cell in lung disease: from COPD to cancer to acute lung injury
Year: 2009


Effects of cigarette smoking on expression of matrix metalloproteinase-12 in airway epithelium of rats
Source: Annual Congress 2010 - Proteases and the matrix
Year: 2010

Cigarette smoke-induced emphysema occurs in the absence of TLR4-signalling in a murine model of COPD
Source: Annual Congress 2008 - Best of lung epithelial cells 2008
Year: 2008



Therapeutic neutralization of the matrikine PGP suppresses the development of lung emphysema in cigarette smoke exposed mice
Source: International Congress 2016 – Mechanisms of disease
Year: 2016