Investigating the role of prostaglandin D2 in airway sensory nerve firing: Relevance to disease

S. Maher, M. Birrell, J. Adcock, M. Wortley, S. Bonvini, M. Grace, M. Belvisi (London, United Kingdom)

Source: Annual Congress 2013 –Preclinical models for the development of new drugs for respiratory diseases
Session: Preclinical models for the development of new drugs for respiratory diseases
Session type: Thematic Poster Session
Number: 687
Disease area: Airway diseases

Congress or journal article abstractE-poster

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
S. Maher, M. Birrell, J. Adcock, M. Wortley, S. Bonvini, M. Grace, M. Belvisi (London, United Kingdom). Investigating the role of prostaglandin D2 in airway sensory nerve firing: Relevance to disease. Eur Respir J 2013; 42: Suppl. 57, 687

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Late Breaking Abstract - Airway sensory innervation is increased in chronic cough
Source: International Congress 2018 – Notable Studies in Asthma
Year: 2018

TRPV4 and activation of airway sensory nerves: The role of ATP
Source: International Congress 2015 – Novel targets and strategies for the treatment of cough, asthma, rhinosinusitis and COPD
Year: 2015

Activation of TRPV4 causes bronchoconstriction: A possible role in respiratory disease?
Source: Annual Congress 2013 –Novel drugs for the treatment of asthma and COPD
Year: 2013


Central role for the TRPV4-ATP-P2X3 axis in sensory nerve activation and the late asthmatic response
Source: International Congress 2016 – Airway pharmacology: drug targets and mode of action
Year: 2016

The muscarinic M3 receptor regulates allergen-induced airway remodeling in mice
Source: Annual Congress 2013 –Asthma drugs: new findings
Year: 2013


Expression of CysLT2 receptors in asthmatic lung, and the roles in bronchoconstriction
Source: International Congress 2014 – Novel approaches and evidence for drug development in respiratory diseases
Year: 2014

Role of the parasympathetic nervous system in the allergen-induced airway sensitization and lung responsiveness
Source: International Congress 2014 – Paediatric asthma: lung function testing and more
Year: 2014

Attenuation of ozone-induced tachypnoea by activation of dopamine D2 receptors in the rat: involvement of vagal bronchopulmonary C fibres
Source: Eur Respir J 2001; 18: Suppl. 33, 408s
Year: 2001

Establishment and evaluation of a new measurement of cough reflex sensitivity: Cough provocation by agonist of TRPA1 (cinnamaldehyde)
Source: International Congress 2014 – Clinical management of lung diseases: from bronchi to pleura
Year: 2014

Experimental airways hyperreactivity and modulation of glutamatergic and nitrergic signalling
Source: Annual Congress 2013 –Novel drugs and biomarkers in respiratory medicine
Year: 2013


Late Breaking Abstract - Role of Muscarinic M3 receptors in bronchial remodelling of severe asthma
Source: International Congress 2017 – Late-breaking findings in asthma and COPD
Year: 2017


Role of TRPV1 and TRPV2 gene polymorphisms in the development of airway hyperresponsiveness to osmotic stimuli in patients with asthma
Source: International Congress 2016 – Role of genetics and exposures in COPD and asthma
Year: 2016


Anti-tussive effects of FAAH inhibition: The role of endocannabinoids and downstream signalling pathways in the inhibition of vagal sensory nerve activation
Source: International Congress 2015 – Novel treatments for cough, asthma, COPD and bronchiectasis
Year: 2015

Neural mechanisms in asthma
Source: ISSN=1025-448x, ISBN=1-904097-26-x, page=138
Year: 2003

Interaction of the glutamatergic and nitrergic signaling system in the airway hyperreactivity
Source: Annual Congress 2012 - Animal models of asthma and COPD and late-breaking abstracts on RCT in asthma and COPD
Year: 2012


Blockade of TSLP pathway alters asthma biomarkers
Source: International Congress 2014 – Clinical trials of drugs for respiratory diseases
Year: 2014

LATE-BREAKING ABSTRACT: A novel role for CCR3 in promoting airways hyperreactivity; Role for CCR3-muscarinic M3 receptor heterodimers
Source: International Congress 2015 – Hot topics on airway diseases: new horizons in treatment
Year: 2015

Effects of dopamine on the elevated airway tone by histamine and methacholine in rabbits
Source: International Congress 2014 – Clinical physiology and respiratory muscles
Year: 2014

Combined loss of M2 and M3 muscarinic acetylcholine receptor (mAChR) function in mutant mice increases serotonin airway responsiveness (AR)
Source: International Congress 2014 – Animal models in respiratory drug development
Year: 2014