Recent advances in the treatment of COPD and acute lung injury

No effect of roflumilast on cardiac repolarization in healthy subjects
R. Hermann, G. Lahu, A. Huennemeyer, D. Knoerzer, T. D. Bethke, W. Haverkamp (Konstanz, Berlin, Germany)
Congress or journal article abstract
Congress or journal article abstract
Experimental therapy with zinc-ions diminishes oxidant lung injury in rats
T. N. Preobrazhenskaya, E. S. Lebedeva (St. Petersburg, Russian Federation)
Congress or journal article abstract
Congress or journal article abstract
Effect of neutrophil elastase inhibitor (ONO-5046) and gabexate mesilate on acid-induced lung injury in rats
S. Yoshikawa, K. Tsushima, T. Koizumi, K. Kubo (Matsumoto, Japan)
Congress or journal article abstract
Congress or journal article abstract
Lipoxin A4 regulates bronchial epithelium responses to acid injury
C. Bonnans, K. Fukunaga, M. A. Levy, B. D. Levy (Boston, St Louis, United States Of America)
Congress or journal article abstract
Congress or journal article abstract
Low systemic exposure of NVA237, an inhaled once-daily anticholinergic bronchodilator, in healthy humans
R. Thomas, E. Eltringham, R. Tansley, S. D. Snape (Merthyr Tydfil, Cambridge, United Kingdom)
Congress or journal article abstract
Congress or journal article abstract
Pharmacokinetics (PK) and pharmacodynamics (PD) of tetomilast in stable COPD subjects
S. Mallikaarjun, S. Shoaf, P. Zhang, K. Mitsui, N. A. Molfino (Rockville, United States Of America)
Congress or journal article abstract
Congress or journal article abstract
Tiotropium reduces subjectively reported sputum production in COPD
D. J. Powrie, T. M. Wilkinson, G. C. Donaldson, J. A. Wedzicha (London, United Kingdom)
Congress or journal article abstract
Congress or journal article abstract
Effects of low dose inhaled carbon monoxide in patients with COPD
D. Bathoorn, D. J. Slebos, D. S. Postma, A. J. M. van Oosterhout, H. A. M. Kerstjens (Groningen, Netherlands)
Congress or journal article abstract
Congress or journal article abstract
Is the hypoxemic effect of formoterol really linked to a shunt-like effect?
S. Centanni, F. Di Marco, P. Santus, M. Verga, A. Pistone, M. Cazzola (Milan, Naples, Italy)
Congress or journal article abstract
Congress or journal article abstract
Effect of flavonoids extracted from Cleome Arabica on human neutrophil elastase activity
R. Kacem (Setif, Algeria)
Congress or journal article abstract
Congress or journal article abstract
Relation of low serum lipid levels with coronary atherosclerosi in COPD patients
H. Ergen, S. Sarac, A. Saygili, Z. Arslan (Istanbul, Adiyaman, Turkey)
Congress or journal article abstract
Congress or journal article abstract
Modulation of sputum gene expression in COPD by fluticasone/salmeterol
E. R. Sutherland, T. A. Moss, A. D. Stevens, J. Pak, R. J. Martin (Denver, United States Of America)
Congress or journal article abstract
Congress or journal article abstract
Inhibition of human lung fibroblast functions by roflumilast N-oxide
S. Boero, M. Silvestri, F. Sabatini, A. Nachira, G. A. Rossi (Genoa, Italy)
Congress or journal article abstract
Congress or journal article abstract
Inhibition of histone acetyltransferases attenuates cytokine and LPS-induced up-regulation of arginase in rat alveolar macrophages
M. Warnken, M. Heideking, S. Matthiesen, K. Racké (Bonn, Germany)
Congress or journal article abstract
Congress or journal article abstract
Effects of TGF-beta and budesonide on MAPK phosphorylation, IL-6/IL-11 secretion, and cell proliferation in human lung fibroblasts
G. Pelaia, L. Gallelli, B. D‘Agostino, A. Vatrella, G. Cuda, D. Fratto, T. Renda, U. Galderisi, E. Piegari, N. Crimi, F. Rossi, M. Caputi, F. S. Costanzo, C. Vancheri, R. Maselli, S. A. Marsico (Catanzaro, Naples, Catania, Italy)
Congress or journal article abstract
Congress or journal article abstract
Expression of transforming growth factors beta (1, 2, 3) and connective tissue growth factor in the peripheral lung from GOLD stage 1-2 COPD patients and smokers with normal lung function
G. Caramori, M. McLeish, A. Lewis, P. Monk, P. Casolari, K. Ito, K. F. Chung, I. M. Adcock, P. J. Barnes, A. Papi (Ferrara, Italy; Cambridge, London, United Kingdom)
Congress or journal article abstract
Congress or journal article abstract
MUC5AC and MUC5B expression in central airways from non-smokers, smokers with normal lung function and GOLD stage 1 and 2 COPD patients
G. Caramori, P. Casolari, M. Saetta, S. Baraldo, K. Ito, L. M. Fabbri, P. J. Barnes, I. M. Adcock, G. Cavallesco, K. F. Chung, A. Papi (Ferrara, Padova, Modena, Italy; London, United Kingdom)
Congress or journal article abstract
Congress or journal article abstract
Roflumilast but not methylprednisolone inhibited cigarette smoke-induced pulmonary inflammation in guinea pigs
M. F. Fitzgerald, D. Spicer, A. E. McAulay, L. Wollin, R. Beume (Stoke Poges, United Kingdom; Konstanz, Germany)
Congress or journal article abstract
Congress or journal article abstract