Source: Annual Congress 2006 - Recent advances in the treatment of COPD and acute lung injury
Disease area: Airway diseases



Rating:

Share or cite this content

Citations should be made in the following way:
G. Pelaia, L. Gallelli, B. D‘Agostino, A. Vatrella, G. Cuda, D. Fratto, T. Renda, U. Galderisi, E. Piegari, N. Crimi, F. Rossi, M. Caputi, F. S. Costanzo, C. Vancheri, R. Maselli, S. A. Marsico (Catanzaro, Naples, Catania, Italy). Effects of TGF-beta and budesonide on MAPK phosphorylation, IL-6/IL-11 secretion, and cell proliferation in human lung fibroblasts. Eur Respir J 2006; 28: Suppl. 50, 3847

Member's Comments

No comment yet.

Related content which might interest you: Effects of endothelin-1 on MAPK activation, IL-6 production and cell proliferation in normal human lung fibroblasts Source: Eur Respir J 2004; 24: Suppl. 48, 454s Year: 2004 Effects of budesonide on p38 MAPK activation, apoptosis and IL-8 secretion, induced by TNF-alpha and Haemophilus influenzae in human bronchial epithelial cells Source: Annual Congress 2010 - Regulation of airway pharmacology Year: 2010 Inhibitory effects of the IL-6 receptor superantagonist SANT7 on MAP kinase phosphorylation and cell proliferation induced by IL-6 and TGF-beta1 in human lung fibroblasts Source: Annual Congress 2008 - Clinical aspects of interstitial lung disease Year: 2008 Transforming growth factor-β inhibition of lung fibroblast proliferation is mediated through prostaglandin E2, via activation of p38 mitogen-activated protein kinase Source: Annual Congress 2005 - Pulmonary hypertension and fibrosis: novel mechanisms Year: 2005 YKL-40 induces IL-8 expression from bronchial epithelium via MAPK (JNK, ERK1/2) and NF-κB pathways, causing bronchial smooth muscle proliferation and migration Source: Annual Congress 2012 - Asthma: mechanisms of airway inflammation Year: 2012 Effects of MAPK inhibitors on H2O2-induced IL-8 production and cell death in primary cultures of human bronchial epithelial cells Source: Eur Respir J 2004; 24: Suppl. 48, 218s Year: 2004 P38 signalling pathway in primary cultures of human bronchial epithelial cells: effects of transforming growth factor-β and pharmacological modulation by budesonide Source: Eur Respir J 2002; 20: Suppl. 38, 571s Year: 2002 Protective effect of MAPK inhibitors and budesonide against apoptosis induced by TGF-β in primary cultures of human bronchial epithelial cells Source: Eur Respir J 2003; 22: Suppl. 45, 394s Year: 2003 TGFβ induced myofibroblast differentiation is independent of p38 activation, but requires TGFβR1 kinase activity and correlates with TGFβ-mediated SMAD signaling and TGFβ-responsive gene expression patterns in human lung fibroblasts Source: Eur Respir J 2004; 24: Suppl. 48, 718s Year: 2004 In vitro profibrotic effects of rapamycin on basal or TGF-β1 induced primary human lung fibroblast: ECM production and turnover, migration and differentiation Source: Annual Congress 2012 - Diffuse parenchymal lung disease I Year: 2012 Differential role of EPAC and PKA in the transduction of cAMP-mediated inhibition of human lung fibroblast proliferation and collagen synthesis Source: Annual Congress 2009 - Pathological remodelling in chronic lung disease: from epithelial-mesenchymal transition to cellular activation Year: 2009 Modulation of bradykinin (BK)-induced lung fibroblast proliferation and differentiation by budesonide (Bud) and formoterol (Form) involves the inhibition of ERK1/2 phosphorylation and Ca2+ mobilization Source: Annual Congress 2009 - Translational models of lung disease Year: 2009 Role of phosphatidylinositol-3-kinase (PI3K) in TGF-β-induced proliferation and differentiation of human lung fibroblasts into myofibroblasts Source: Annual Congress 2011 - Genetic and molecular background in pulmonary fibrosis Year: 2011 Thrombin induces stomatin-like protein 2 (STOML2) expression and IL-8/CXCL8 release by ROCK, JNK, and PEA3 pathways in human lung epithelial cells Source: Virtual Congress 2020 – Asthma science: novel targets and mechanisms Year: 2020 N-Acetylcysteine inhibits eotaxin and MCP-1 release in human airway smooth muscle cells in vitro through the inhibition of ROS production, resulting in a decrease of p38 MAP kinase activation Source: Eur Respir J 2002; 20: Suppl. 38, 170s Year: 2002 Interleukin-8 stimulates human airway epithelial cell proliferation through EGFR transactivation Source: Eur Respir J 2003; 22: Suppl. 45, 561s Year: 2003 Budesonide and formoterol rapidly and effectively inhibit ERK1/2 phosphorylation in bradykinin-stimulated human lung fibroblasts Source: Annual Congress 2008 - Novel experimental approaches to understanding asthma and COPD II Year: 2008 Exposure to LPS induces the upregulation of p38 MAPK in human bronchial epithelium in vivo Source: Eur Respir J 2003; 22: Suppl. 45, 459s Year: 2003 Cell cycle regulation of IPF-derived lung fibroblasts is dependent on RhoA signalling Source: Eur Respir J 2005; 26: Suppl. 49, 102s Year: 2005 MAPK inhibition modulates Hsp27 phosphorylation and glutathione in lung epithelial cells Source: Eur Respir J 2006; 28: Suppl. 50, 192s Year: 2006