ERS International Congress, Paris 2018

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Citations should be made in the following way: Authors. Title. Eur Respir J 2018; 52: Suppl. 62, abstract number.

Organoids and pluripotent stem cells

Symposium
Chairs: S. Bartel (Groningen, Netherlands), P. Hiemstra (Leiden, Netherlands)
Aims: to present and discuss (i) the methods by which gut and lung organoids can be cultured and their uses as disease models in translational research, (ii) the biological basis, methodological approaches and applications of Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR/Cas) gene editing, and (iii) the technical approaches targeting epigenetic mechanisms that can be used to reprogram gene expression.

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Intestinal organoids as ex vivo models for personalised medicine in cystic fibrosis J. Beekman (Utrecht, Netherlands)
The use of bronchospheres to study chronic lung diseases M. Konigshoff (Denver, United States of America)
Genome modification with CRISPR/Cas P. Harrison (Cork, Ireland)
The potential of epigenetic editing in chronic lung disease M. Rots (Groningen, Netherlands)
Optimizing experimental research in respiratory diseases: an ERS Statement M. Kolb (Hamilton (ON), Canada)