Effect of roflumilast on exacerbations in patients with severe COPD and a prior history of hospitalization taking combination therapy
Fernando J. Martinez (Ann Arbor, United States of America), Fernando J. Martinez, Peter M.A. Calverley, Udo-Michael Goehring, Rachel Hodge, Leonardo M. Fabbri, Klaus F. Rabe
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AZD7624, an inhaled p38 inhibitor for COPD, attenuates lung and systemic inflammation after LPS Challenge in humans
Naimish Patel (Waltham, United States of America), Naimish Patel, Danen Cunoosamy, Tove Hegelund-Myrback, Rikard Pehrson, Ziad Taib, Paul Jansson, Sofia Lundin, Steven Greenaway, Graham Clarke, Leonard Siew
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Favorable human safety, pharmacokinetics and pharmacodynamics of the autotaxin inhibitor GLPG1690, a potential new treatment in COPD
Ellen van der Aar (Mechelen, Belgium), Ellen Van der Aar, Liesbeth Fagard, Julie Desrivot, Sonia Dupont, Bertrand Heckmann, Roland Blanque, Lien Gheyle, Jovica Ralic, Frédéric Vanhoutte
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TSPO a new anti-inflammatory target in the airway of COPD
Romain JEAN (Montpellier, France), Romain Jean, Estelle Bribes, Lucie Knabe, Aurélie Fort-Petit, Isabelle Vachier, Pascal Chanez, Arnaud Bourdin
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Targeted silencing of master transcription factor SPDEF to reduce mucus production in airway diseases by epigenetic editing
Juan Song (Groningen, Netherlands), Juan Song, Karolin Meyer, Loes E.M. Kistemaker, Reinoud Gosens, Pieter S. Hiemstra, Marianne Rots, Machteld Hylkema
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Anti-inflammatory effects of resveratrol analogues in cellular models of airway inflammation
Samuel C M Yeo (London, United Kingdom), Samuel C.M. Yeo, Peter S. Fenwick, Peter J. Barnes, Louise E. Donnelly
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Mitochondrial reactive oxygen species and glycolysis in airway smooth muscle cell proliferation in COPD
Charalambos Michaeloudes (London, United Kingdom), Charalambos Michaeloudes, Paul Kirkham, Ian M. Adcock, Kian Fan Chung
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Carbocisteine attenuates influenza virus A replication in the bronchoalveolar lavage fluids of virus-infected mice
Shuichiro Maruoka (Tokyo, Japan), Shuichiro Maruoka, Sotaro Shikano, Yasuhiro Gon, Kazumichi Kuroda, Kaori Soda, Eriko Tsuboi, Ikuko Takeshita, Kazufumi Shimizu, Shu Hashimoto
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