Source: International Congress 2015 – Advances in the future treatment of COPD
Disease area: Airway diseases



Rating:

Share or cite this content

Citations should be made in the following way:
Juan Song (Groningen, Netherlands), Juan Song, Karolin Meyer, Loes E.M. Kistemaker, Reinoud Gosens, Pieter S. Hiemstra, Marianne Rots, Machteld Hylkema. Targeted silencing of master transcription factor SPDEF to reduce mucus production in airway diseases by epigenetic editing. Eur Respir J 2015; 46: Suppl. 59, 486

Member's Comments

No comment yet.

Related content which might interest you: IFNγ influences bronchial epithelial anti-viral immune responses via inducible epigenetic control of histone methylation of the RIG-I promoter Source: International Congress 2015 – The multiple faces of host defense Year: 2015 Asthma and diabetes: Possible markers of their co-existence. The possible role of transcription factors GATA-3 and T-bet and negative regulator of transcription SOCS1 in the worsening of asthma Source: International Congress 2015 – Translational research in respiratory care: new findings Year: 2015 Transcription factor p63 regulates differentiation- and repair-related genes in primary human bronchial epithelial cells: Implications for airway remodeling in asthma Source: Annual Congress 2011 - Epithelial cells: role in health and disease Year: 2011 The expression of the negative regulator of gene transcription SOCS3 as the crucial marker in the asthma pathogenesis Source: International Congress 2014 – New mechanisms in the pathogenesis of asthma and other lung diseases Year: 2014 Airway epithelial cell IP-10 production is regulated by miR-31 via the transcription factor IRF-1 Source: International Congress 2015 – Immunomodulation: basic science and clinical aspects Year: 2015 Enhanced inflammatory gene expression in bronchial epithelial cells from asthmatic patients: Attenuation by a Brd4 mimic Source: International Congress 2014 – Novel targets and drugs for asthma and COPD Year: 2014 The crucial role of the expression of negative regulator of gene transcription SOCS5 in asthma pathogenesis Source: Annual Congress 2013 –Translational research to bridge the need within clinical decision making Year: 2013 The role of suppressor of cytokine signalling 1 (SOCS1) in virus-induced asthma exacerbations Source: International Congress 2016 – Viral infections in different respiratory conditions: from the bedside to the lab Year: 2016 The capacity of human airway epithelium to regulate T cell proliferation is reduced in asthma Source: International Congress 2015 – Asthma mechanisms and management Year: 2015 Periostin: A key contributor to changes in the epithelial phenotype in asthma? Source: International Congress 2015 – Clincal aspects of asthma: monitoring and mechanisms Year: 2015 Reduced MicroRNA-19a causes constitutive high expression of PRMT1 and remodeling in asthma Source: International Congress 2016 – New therapies and therapeutic targets Year: 2016 Leukotriene E4 affects expression of genes involved in inflammatory, remodelling and mitogenic responses in human bronchial epithelial cells Source: International Congress 2016 – Novel insights into alveolar and bronchial epithelial cell injury and repair Year: 2016 Changes in epithelial barrier components E-cadherin, Beta-catenin, EGR with steroid treatment in murine model of asthma Source: International Congress 2015 – Therapeutic approaches in inflammatory lung disease Year: 2015 Egr-1 regulates muc5ac expression through activator protein-1 (AP-1) in chronic airway inflammation diseases Source: International Congress 2015 – Translational studies in airway cell biology Year: 2015 Glucocorticoid-induced transcriptional regulators in human airway cells and airways Source: International Congress 2016 – Studies in airway cell biology Year: 2016 PCDH1: Localization and cell-adhesion in airway epithelium in asthma Source: International Congress 2015 – Translational studies in airway cell biology Year: 2015 Transcription factor EB (TFEB) regulates cigarette smoke extract (CSE)-induced cellular senescence Source: International Congress 2014 – Effect of cigarette smoke on cell behaviour: cell biology, signalling and senescence Year: 2014 LSC 2014 abstract - Azithromycin lowers mucin production by increasing FOXA2 expression in an IL-13-induced MUC5AC expression model in human bronchial epithelial cells Source: International Congress 2014 – Mechanistic studies of the airway epithelium Year: 2014 Potential role of SPARC, a downstream mediator of TGF-b in chronic airways disease Source: International Congress 2015 – Airway remodelling: recent developments Year: 2015