Role of genetics and exposures in COPD and asthma

Thematic Poster
Chairs: Judith M. Vonk (Groningen, Netherlands), Erik Melén (Stockholm, Sweden), Morten Dahl (Koege, Denmark), Florence Demenais (Paris, France)
ALOX15 gene polymorphisms in Japanese patients with aspirin-exacerbated respiratory disease (AERD)
Ryosuke Souma (Koshigayashi Saitama, Japan), Ryosuke Souma, Kenya Koyama, Akemi Koyama, Shyuzo Abe, Junichiro Morioka, Kei Sugitate, Takayoshi Fujimatsu, Hajime Arifuku, Kentaro Nakano, Tomoshige Wakayama, Hideyuki Satoh, Hirokuni Hirata, Kumiya Sugiyama Sugiyama, Yasutsugu Fukushima
Congress or journal article abstract
Congress or journal article abstract
Role of TRPV1 and TRPV2 gene polymorphisms in the development of airway hyperresponsiveness to osmotic stimuli in patients with asthma
Denis Naumov (Blagoveshchensk, Amur Oblast, Russian Federation), Denis Naumov, Juliy Perelman, Anna Prikhodko, Victor Kolosov, Elizaveta Sheludko
Congress or journal article abstractE-poster
Congress or journal article abstractE-poster
Replication association study IREB2, CHRNA5, CHRNA3, CHRNB4, FAM13A, HTR4, and HHIP genes polymorphisms with chronic obstructive pulmonary disease in Tatar population from Russia
Guly F Korytina (Ufa, Russian Federation), Guly F. Korytina, Leysan Z. Akhmadishina, Kristina Y. Knyazeva, Yuliya G. Aznabaeva, Tatyana V. Viktorova, Shamil Z. Zagidullin
Congress or journal article abstractE-poster
Congress or journal article abstractE-poster
Systematic dissection of ORMDL3 function in vitro and in vivo
Youming Zhang (London, United Kingdom), Youming Zhang, Charlotte Dean, Stephan Loeser, Lisa Gregory, Clare Lloyd, Miriam Moffatt, William Cookson
Congress or journal article abstract
Congress or journal article abstract
Transgenerational epigenetics: Maternal and grandmaternal gestational smoking influences DNA methylation of the AHRR gene
Veeresh K. Patil (Newport, United Kingdom), Veeresh K. Patil, Nandini Mukherjee, Gabrielle Lockett, Hongmei Zhang, Wilfried Karmaus, John W. Holloway, S. Hasan Arshad
Congress or journal article abstract
Congress or journal article abstract
Cardio-metabolic disorder in grandparents associated with asthma in offspring: Results from a European 3-generation analysis
Anne-Elie Carsin (Barcelona, Spain), Anne-Elie Carsin, Francisco Real, Xavier Basagana, Simone Accordini, Shyamali Dharmage, Vivi Schlünssen, Bryndís Benediktsdóttir, Benedicte Leynaert, Christer Janson, Jordi Sunyer, Julia Dratva, Debbie Jarvis, Cecilie Svanes
Congress or journal article abstractE-poster
Congress or journal article abstractE-poster
Association between candidate gene polymorphisms and asthma severity in adults. A Bayesian analysis
Lucia Calciano (Verona, Italy), Lucia Calciano, Laura Portas, Cristina Bombieri, Marcello Ferrari, Giovanni Malerba, John R. Thompson, Simone Accordini
Congress or journal article abstract
Congress or journal article abstract
Effects of ICS/LABA treatment on hyperinflation and genome wide gene-expression in upper airway epithelium in severe COPD
Kai Imkamp (Groningen, Netherlands), Kai Imkamp, Alen Faiz, Erica van der Wiel, Ilse Boudewijn, Gerard Koppelman, Corry-Anke Brandsma, Huib Kerstjens, Wim Timens, Sebastiaan Vroegop, Henk Pasma, Wim Boersma, Pascal Wielders, Frank van den Elshout, Khaled Mansour, Katrina Steiling, Avrum Spira, Marc Lenburg, Irene Heijink, Dirkje Postma, Maarten van den Berge
Congress or journal article abstractE-poster
Congress or journal article abstractE-poster
Alpha-1 antitrypsin phenotype determination using sebia isoelectrofocusing on dried blood spot samples
Stefania Ottaviani (Tromello, Italy), Stefania Ottaviani, Valentina Barzon, Laura Divizia, Angelo Guido Corsico, Ilaria Ferrarotti
Congress or journal article abstractE-poster
Congress or journal article abstractE-poster
Influence of ADRβ2 gene polymorphism on the level of bronchial obstruction and body mass index in patients with bronchial asthma
Vladyslava Kmyta (Sumy, Ukraine), Vladyslava Kmyta, Anna Bondarkova, Lyudmyla Prystupa
Congress or journal article abstractE-poster
Congress or journal article abstractE-poster
Variants of apelin gene and COPD
Ender Coşkunpınar (Istanbul, Turkey), Ender Coskunpinar, Engin Aynaci, Abdullah Melekoglu, Pinar Yildiz
Congress or journal article abstract
Congress or journal article abstract
Detection of alpha1-antitrypsin deficiency in a European country without national registry yet
Leonor Meira (Leça da Palmeira, Portugal), Leonor da Hora Lopes Meira, Rita Boaventura, Susana Seixas, Maria Sucena
Congress or journal article abstract
Congress or journal article abstract
Characterization of microbiome in patients with lung cancer comparing with benign mass-like lesions
Ji Soo Choi (Seoul, Republic of Korea), Jisoo Choi, Moo Suk Pack, Dong Eun Yong, Ji Yeon Sung, Sang Hoon Lee, Eun Hye Lee, Ji Eun Park, Mi Hwa Shin
Congress or journal article abstractE-poster
Congress or journal article abstractE-poster
meQTL analysis of asthma GWAS loci and DNA methylation
Ashish Kumar (Stockholm, Sweden), Ashish Kumar, Cilla Söderhäll, Simon Merid, Chengjian Xu, Olena Gruzieva, Gerard Koppelman, Juha Kere, Göran Pershagen, Erik Melén
Congress or journal article abstractE-poster
Congress or journal article abstractE-poster
Interactions of genetic variants and DNA-M of TSLP modify the eczema risk
Rumana Siddique (Germantown, United States of America), Rumana Siddique, Hongmei Zhang, Hasan Arshad, John Holloway, Wilfried Karmaus
Congress or journal article abstract
Congress or journal article abstract
LATE-BREAKING ABSTRACT: Occupational exposure to pesticides is associated with differential DNA methylation
Diana van der Plaat (Groningen, Netherlands), Diana van der Plaat, Kim de Jong, Judith Vonk, Cleo van Diemen, Ivana Nedeljkovic, Najaf Amin, Hans Kromhout, Roel Vermeulen, Cornelia van Duijn, Dirkje Postma, Marike Boezen
Congress or journal article abstract
Congress or journal article abstract
LATE-BREAKING ABSTRACT: NO2 and lung function: Mediation by DNA methylation
Ana Julia de Faria Coimbra Lichtenfels (Groningen, Netherlands), Ana Julia de Faria Coimbra Lichtenfels, Diana A. van der Plaat, Kim de Jong, Ronald P. Stolk, Bert Brunekreef, Judith M. Vonk, H. Marike Boezen
Congress or journal article abstract
Congress or journal article abstract
LATE-BREAKING ABSTRACT: Inhaled diesel exhaust alters immune response proteins in the bronchial secretome in humans
Neeloffer Mookherjee (Winnipeg, Canada), Neeloffer Mookherjee, Peyman Ezzati, Victor Spicer, Christopher Carlsten
Congress or journal article abstractE-poster
Congress or journal article abstractE-poster
LATE-BREAKING ABSTRACT: Effects of rare SERPINA1 variants on emphysema and airtrapping in SPIROMICS
Victor Ortega (Winston-Salem, United States of America), Victor Ortega, Xingnan Li, Wanda O’Neal, R. Graham Barr, David Couper, Meilan Han, Richard Kanner, Eric Kleerup, Fernando Martinez, Stephen Peters, Stephen Rennard, Prescott Woodruff, Eric Hoffman, Deborah Meyers, Eugene Bleecker
Congress or journal article abstract
Congress or journal article abstract
LATE-BREAKING ABSTRACT: Interaction of 17q21 variants with breastfeeding in relation to respiratory symptoms in infancy
Olga Gorlanova (Aesch, Switzerland), Olga Gorlanova, Jakob Usemann, Antoaneta A. Toncheva, Philipp Latzin, Michael Kabesch, Erika von Mutius, Urs Frey
Congress or journal article abstract
Congress or journal article abstract