Clinical Trial presentation and discussion "Cysteinyl leukotrienes and paediatric asthma: a new horizon or a blind alley?"
Symposium Chairs: B. Rottier (Groningen, Netherlands), I. Pavord (Leicester, United Kingdom)
Aims: Drawing on the first presentation of the results of a large randomised placebo controlled trial of intermittent montelukast for preschool asthma, this symposium will review the pathways whereby cysteinyl leukotrienes (cLT) affect airway cells, the clinical relevance of polymorphisms of cLT genes and the evidence to support the use of cLT modifying therapies in paediatric asthma.