Source: Annual Congress 2006 - Inflammatory markers and experimental studies in occupational and environmental diseases
Disease area: Airway diseases



Rating:

Share or cite this content

Citations should be made in the following way:
R. M. Mroz, R. P. F. Schins, H. Li, A. L. Jimenez, E. M. Drost, W. MacNee, K. Donaldson (Edinburgh, United Kingdom; Düsseldorf, Germany; Bialystok, Poland). Nanoparticle-driven DNA damage mimics irradiation by inducing growth arrest and phosphorylation of 53BP-1, BRCA1 and H2A.X. Eur Respir J 2006; 28: Suppl. 50, 3634

Member's Comments

No comment yet.

Related content which might interest you: Growth arrest and apoptosis induced by E2F-1 is associated with downregulation of p21 and uncoupling of S-phase and mitosis in NSCLC Source: Eur Respir J 2001; 18: Suppl. 33, 475s Year: 2001 Benzo[a]pyrene increase ubiquitination of p21 protein following the stabilization of p53 and the expression of p21 Source: Eur Respir J 2002; 20: Suppl. 38, 482s Year: 2002 Nanoparticle-driven DNA damage mimics irradiation-related carcinogenesis pathways Source: Eur Respir J 2008; 31: 241-251 Year: 2008 Phosphorylation of p53 and H2AX histone variant in response to air pollution particulates and oxidative stress Source: Eur Respir J 2004; 24: Suppl. 48, 106s Year: 2004 Cytokine-induced EGFR protein release in BEAS-2B cells; relation with histone acetylation and methylation status Source: Eur Respir J 2005; 26: Suppl. 49, 556s Year: 2005 Triptolide enhances radiosensitivity of lung cancer cells via G2/M arrest and autophage Source: Virtual Congress 2020 – Biological mechanisms of lung cancer Year: 2020 Involvement of proteasome inhibition and p53 accumulation in epithelial apoptosis of lung injury Source: Eur Respir J 2005; 26: Suppl. 49, 101s Year: 2005 Counteracting the ET-1 induced pathological cell proliferation by bosentan – nuclear expression of cell cycle inhibitors p21 (waf1) and p27 (kip1) induces G1-arrest in pulmonary artery smooth muscle cells Source: Annual Congress 2008 - Pulmonary vascular biology Year: 2008 Oxidative stress-mediated decrease in histone deacetylase activity is attenuated by N-acetyl-L-cysteine but not by Iκ-B kinase inhibition in alveolar epithelial cells Source: Eur Respir J 2004; 24: Suppl. 48, 29s Year: 2004 PP221 – EZH2-dependent transcriptional complex promotes aberrant epithelial remodelling after injury Source: ERS Lung Science Conference 2021 Year: 2021 Nadroparin inhibits A549 human adenocarcinoma cell proliferation through down-regulation of cyclin B1 and G2/M phase cell-cycle arrest Source: Annual Congress 2010 - Pathology of lung cancer Year: 2010 Decreased expression of DNA synthesis repair recombination proteins in lungs of senescence accelerated mouse (SAM) Source: Eur Respir J 2003; 22: Suppl. 45, 73s Year: 2003 Inhibition of hypoxia-induced phenotype alterations through epithelial-mesenchymal transition (EMT) in lung cancer by gene modulation of phosphorylation sites in tumor suppressor PTEN Source: Annual Congress 2011 - Lung cancer: molecular pathology and functional genomics Year: 2011 Effects of p27Kip1 on cell cycle status and viability in A549 lung adenocarcinoma cells Source: Eur Respir J 2004; 23: 665-670 Year: 2004 Effect of oxidative stress on amplified inflammation via dissociation of co-repressors and HDAC2 Source: Annual Congress 2007 - Inflammatory cell biology Year: 2007 The inhibition of fas-mediated apoptosis of lung alveolar epithelial cells by cyclin dependent kinase inhibitor p21 Source: Eur Respir J 2001; 18: Suppl. 33, 358s Year: 2001 Retinoic acid abrogation of TNF-alpha-induced growth arrest in lung alveolar epithelial cells is linked to p21 (CIP1) downregulation Source: Eur Respir J 2001; 18: Suppl. 33, 477s Year: 2001 Oxidative stress alters histone acetylation and deacetylation: potential mechanism in inflammatory gene transcription Source: Eur Respir J 2001; 18: Suppl. 33, 182s Year: 2001 Simultaneous assessment of p21/waf1, p53, pRb, mdm2 and cyclin D1in NSCLC cells Source: Eur Respir J 2005; 26: Suppl. 49, 226s Year: 2005 Nanoparticles driven DNA damage cell signalling mimicks irradiation model of cancerogenesis Source: Eur Respir J 2005; 26: Suppl. 49, 151s Year: 2005