Why is allograft formation in SCID mice slow in lung adenocarcinoma cell line with EGFR activating mutation?

N. Nukiwa, M. Xie, T. Fukuhara, C. Treda, T. Kikuchi, M. Ebina, T. Nukiwa (Sendai, Japan)

Source: Annual Congress 2010 - New insights in the pathology of lung cancer
Session: New insights in the pathology of lung cancer
Session type: Oral Presentation
Number: 5168
Disease area: Thoracic oncology

Congress or journal article abstractE-poster

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
N. Nukiwa, M. Xie, T. Fukuhara, C. Treda, T. Kikuchi, M. Ebina, T. Nukiwa (Sendai, Japan). Why is allograft formation in SCID mice slow in lung adenocarcinoma cell line with EGFR activating mutation?. Eur Respir J 2010; 36: Suppl. 54, 5168

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Interleukin-17 enhances the net angiogenic potential and in vivo growth of human non-small cell lung cancer in SCID mice through promoting CXCR-2-dependent angiogenesis
Source: Eur Respir J 2004; 24: Suppl. 48, 79s
Year: 2004

Tiotropium inhibits growth of squamous cell lung carcinoma (SCC) cell lines in vitro and also inhibits SCC growth in vivo in nude mice by inhalation
Source: Annual Congress 2010 - New insights in the pathology of lung cancer
Year: 2010


Effects of ASCL1 expression on tumorigenesis and immune cell infiltration in a syngenic mouse model of lung adenocarcinoma
Source: International Congress 2019 – Biology of lung cancer
Year: 2019


Inhibition of tumor growth and metastatic lung tumors in mice by adenovirus-mediated interferon-β gene therapy
Source: Eur Respir J 2003; 22: Suppl. 45, 199s
Year: 2003

Increased proliferation of type 2 alveolar epithelial cells in a pneumonectomy model mice with a deletion of p16ink4a gene.
Source: International Congress 2018 – Regenerative and anti-fibrotic approaches
Year: 2018



Is caveolin-1 lost as a tumor suppressor gene in lung carcinoma?
Source: Annual Congress 2004 - Lung development and cancer
Year: 2004


Ghrelin does not influence cancer progression in a lung cancer cell line and mice with lung adenocarcinoma
Source: International Congress 2018 – Lung cancer: from the bench to the bedside
Year: 2018

Macrophages within NSCLC tumour islets are predominantly of a cytotoxic M1 phenotype associated with extended survival
Source: Eur Respir J 2009; 33: 118-126
Year: 2009



Tissue inhibitor of metalloproteinase 3 inhibits growth of lung cancer tumours in nude mice
Source: Eur Respir J 2004; 24: Suppl. 48, 704s
Year: 2004

Functional expressions of EGFP/LKB1 and its kinase domain induced apoptosis and enhanced chemosensitivity in lung cancer cell lines
Source: Eur Respir J 2004; 24: Suppl. 48, 5s
Year: 2004

Adenovirus-mediated interferon-beta gene therapy inhibits tumor growth and inhibits metastatic lung tumors in mice
Source: Eur Respir J 2002; 20: Suppl. 38, 186s
Year: 2002

In vivo models of human airway epithelium repair and regeneration
Source: Eur Respir Rev 2005; 14: 131-136
Year: 2005



Her/2 neu and p53 expression in patients with non-small cell lung cancer predict shortened survival
Source: Annual Congress 2010 - Biomarkers for lung cancer
Year: 2010

P2X7 receptor regulates cell survival, inflammation processes and proliferation of lung carcinoma cells
Source: International Congress 2019 – Novel insights from in vitro and in vivo models of lung disease
Year: 2019

Inhibition of insulin-like growth factor type I (IGF-I) gene in A549 human lung cancer cell line enhances cell apoptosis and causes phenotype changes relevant to increased tumor susceptibility to immune system
Source: Eur Respir J 2007; 30: Suppl. 51, 715s
Year: 2007

MiR-34a favours macrophage polarization switch from M2 to M1 phenotype in non small cell lung cancer (NSCLC)
Source: Virtual Congress 2020 – Molecular alterations and immunology in lung cancer
Year: 2020


ADAM28 deletion in mice impacts lung metastasis formation
Source: International Congress 2018 – Lung cancer: novel molecular markers and mechanisms
Year: 2018




Specific plasmids encoding shRNA molecules directed against growth factor receptors in cell proliferation inhibition and induction phenotype changes relevant to enhancement of anti-tumor immunity. Model of human non-small (NSCLC) and small (SCLC) cell lung cancer lines
Source: Annual Congress 2010 - Pathology of lung cancer
Year: 2010

Clinical features associated with epidermal growth factor receptor and K-RAS gene mutations in non-small cell lung cancer
Source: Eur Respir J 2006; 28: Suppl. 50, 811s
Year: 2006