PDE4 inhibition prevents corticosteroid-resistant lung inflammation induced by cigarette smoke exposure in mice Source: Annual Congress 2009 - Highlighting the epithelial cell in lung disease: from COPD to cancer to acute lung injury Year: 2009
Potent anti-inflammatory effects of the highly selective iNOS inhibitor Byk402750 in a mouse model of cigarette smoke induced inflammation Source: Annual Congress 2008 - Novel experimental approaches to understanding asthma and COPD Year: 2008
Involvement of MMP-12 and phosphodiesterase type 4 in cigarette smoke-induced inflammation in mice Source: Eur Respir J 2006; 27: 1102-1109 Year: 2006
Inhibition of lung inflammation by a protein epitope mimetic (PEM) neutrophil elastase inhibitor, POL6014, in a sub-chronic tobacco smoke (TS) model in mice Source: Annual Congress 2013 –Novel drugs for the treatment of asthma and COPD Year: 2013
A neutrophil elastase inhibitor reduces cigarette smoke-induced remodelling of lung vessels Source: Eur Respir J 2003; 22: 77-81 Year: 2003
Roflumilast inhibited emphysema development in mice exposed to cigarette smoke Source: Eur Respir J 2005; 26: Suppl. 49, 204s Year: 2005
Cilomilast, a second generation phosphodiestease 4 inhibitor, in combination with PGE2 attenuates fMLP, IL-8 and cigarette smoke-induced effects on the mechanical and functional properties of neutrophils Source: Eur Respir J 2001; 18: Suppl. 33, 161s Year: 2001
Attenuation of lung inflammation and emphysema induced by cigarette smoke exposure in CXCR3 knockout mice Source: Annual Congress 2008 - Cell biology of asthma and COPD Year: 2008
Caspase-7 knockout mice are not protected against cigarette smoke-induced inflammation Source: Annual Congress 2010 - Novel mechanisms in COPD Year: 2010
Blocking IL-20 pathway limits the development of bacteria induced exacerbation in mice chronically exposed to cigarette smoke. Source: International Congress 2018 – Disease exacerbations from a molecular point of view Year: 2018
Matrix metalloproteinase 12 (MMP-12) expression in human monocyte-derived macrophages is enhanced by exposure to cigarette smoke and is resistant to suppression by dexamethasone Source: Eur Respir J 2004; 24: Suppl. 48, 107s Year: 2004
Enhanced neutrophilic inflammation in IL-10-deficient mice exposed to cigarette smoke via TNF-α regulation Source: Annual Congress 2012 - Recent progress in mechanisms and diagnostics of COPD and asthma Year: 2012
Effect of non-steroidal anti-inflammatory drugs on neutrophil recruitment, p38 map kinase phosphorylation and NF-κB activation in lung from mice exposed to cigarette smoke Source: Annual Congress 2007 - Molecular pathogenesis: focus on COPD and asthma Year: 2007
IL-10 resolves the neutrophilic inflammation in mice exposed to cigarette smoke Source: Annual Congress 2011 - Recent developments in COPD Year: 2011
Neu-164, a novel antioxidant and anti-inflammatory compound, reduces cigarette smoke-induced lung inflammation Source: Annual Congress 2008 - COPD Year: 2008
Deficiency in neutrophil serine proteases protects mice from the development of cigarette smoke-induced emphysema Source: Annual Congress 2010 - Proteases and the matrix Year: 2010
Therapeutic neutralization of the matrikine PGP suppresses the development of lung emphysema in cigarette smoke exposed mice Source: International Congress 2016 – Mechanisms of disease Year: 2016
Cigarette smoke in mice, rats and guinea-pigs: value to the study of pathogenic factors involved in COPD Source: Annual Congress 2005 - PG11 - Experimental models for COPD and asthma Year: 2005
Distinct effect of IRAK-M on airway inflammation induced by exposure to LPS or cigarette smoking Source: International Congress 2017 – Cigarette smoke and particulate matter: basic science and clinical aspects Year: 2017
Ceramide-1-phosphate attenuates cigarette smoke induce lung inflammation Source: Annual Congress 2013 –Cell biology and murine models of asthma and inflammation Year: 2013