Caspase-7 knockout mice are not protected against cigarette smoke-induced inflammation

N. S. Pauwels, T. Demoor, T. Vanden Berghe, L. L. Dupont, K. R. Bracke, G. F. Joos, P. Vandenabeele, G. G. Brusselle (Ghent, Belgium)

Source: Annual Congress 2010 - Novel mechanisms in COPD
Session: Novel mechanisms in COPD
Session type: Thematic Poster Session
Number: 4329
Disease area: Airway diseases

Congress or journal article abstractE-poster

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
N. S. Pauwels, T. Demoor, T. Vanden Berghe, L. L. Dupont, K. R. Bracke, G. F. Joos, P. Vandenabeele, G. G. Brusselle (Ghent, Belgium). Caspase-7 knockout mice are not protected against cigarette smoke-induced inflammation. Eur Respir J 2010; 36: Suppl. 54, 4329

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Ablation of ADAM17 protects against cigarette smoke-induced emphysema in mice
Source: International Congress 2019 – Effects of environmental exposures in lung pathology and the underlying mechanisms
Year: 2019

Attenuation of lung inflammation and emphysema induced by cigarette smoke exposure in CXCR3 knockout mice
Source: Annual Congress 2008 - Cell biology of asthma and COPD
Year: 2008


Transgenic expression of human glutathione peroxidase-1 prevents cigarette smoke-induced inflammation and emphysema formation in mice
Source: Eur Respir J 2007; 30: Suppl. 51, 133s
Year: 2007

Deficiency in neutrophil serine proteases protects mice from the development of cigarette smoke-induced emphysema
Source: Annual Congress 2010 - Proteases and the matrix
Year: 2010

Enhanced neutrophilic inflammation in IL-10-deficient mice exposed to cigarette smoke via TNF-α regulation
Source: Annual Congress 2012 - Recent progress in mechanisms and diagnostics of COPD and asthma
Year: 2012

PDE4 inhibition prevents corticosteroid-resistant lung inflammation induced by cigarette smoke exposure in mice
Source: Annual Congress 2009 - Highlighting the epithelial cell in lung disease: from COPD to cancer to acute lung injury
Year: 2009


LATE-BREAKING ABSTRACT: BRP-39 contribute to cigarette smoke-induced inflammation and emphysema in mice and humans
Source: Annual Congress 2009 - Airway cell biology
Year: 2009


RAGE and cigarette smoke-induced pulmonary lesions: a chronic study on genetically manipulated mice
Source: Annual Congress 2009 - From emphysema to fibrosis: mechanisms of cellular remodelling in the diseased lung
Year: 2009

Oral presentation: SOD3 protects cigarette smoke-induced emphysema associated with reduction of extracellular matrix fragmentation in mice
Source: Lung Science Conference 2010 - Biology of gene-environment interactions in the lung
Year: 2010

LPS accelerates cigarette smoke-induced deterioration in respiratory function and airway inflammation in mice
Source: Annual Congress 2007 - New treatments for asthma and COPD - experimental evidence
Year: 2007


Role of ß2-adrenergic receptor in cigarette smoke-induced COPD in mice
Source: International Congress 2018 – Functional genomics and COPD: new challenges
Year: 2018

Cigarette smoke results in accelerated airspace enlargement in Smad3 KO mice through increased alveolar cell apoptosis
Source: Annual Congress 2010 - Emerging mechanisms in lung injury
Year: 2010

Mitochondria-targeted H2S suppresses and reverses cigarette smoke-induced inflammasome activity and lung injury in experimental COPD
Source: ERS Lung Science Conference 2020
Year: 2020

Disruption of pulmonary lipid homeostasis drives cigarette smoke-induced lung inflammation in mice
Source: Eur Respir J 2015; 46: 1451-1460
Year: 2015



Lack of RTP801, a suppressor of the mTOR pathway, attenuates cigarette smoke-induced pulmonary injuries in mice
Source: Eur Respir J 2007; 30: Suppl. 51, 140s
Year: 2007

A selective MMP-12 inhibitor, MV062926, reduces inflammatory responses to cigarette smoke in mice
Source: Annual Congress 2010 - Pre-clinical models of airways disease
Year: 2010



Effects of thioredoxin-1 on accelerated emphysema progression in cigarette smoke-exposed mice challenged with polyinosine-polycytidylic acid
Source: Annual Congress 2010 - Novel mechanisms in COPD
Year: 2010


Irisin secreted from muscle by exercise ameliorates emphysema of cigarette smoke-induced COPD in mice.
Source: International Congress 2019 – New molecular signatures in COPD, lung cancer and a1-antitrypsin deficiency
Year: 2019


Tiotropium inhalation prevents acute cigarette smoke-induced airway inflammation in mice
Source: Annual Congress 2009 - Airway inflammation and host defence
Year: 2009

Ninjin-yoeito ameliorates cigarette smoke-induced skeletal muscle complications in mice
Source: Virtual Congress 2020 – Clinical and basic pharmacology for COPD
Year: 2020