Corticosteroids reduce pro-inflammatory cytokine expression in airway smooth muscle cells via upregulation of MAPK phosphatase-1 and inhibition of p38 MAPK signalling Source: Eur Respir J 2005; 26: Suppl. 49, 713s Year: 2005
The pan janus kinase (JAK) inhibitor KN-002 suppresses inflammatory mediator release from severe asthma bronchial epithelial cells. Source: Virtual Congress 2021 – Airway pharmacology: translational and basic science Year: 2021
YKL-40 induces IL-8 expression from bronchial epithelium via MAPK (JNK, ERK1/2) and NF-κB pathways, causing bronchial smooth muscle proliferation and migration Source: Annual Congress 2012 - Asthma: mechanisms of airway inflammation Year: 2012
Involvement of NFkB activation and c-JUN phosphorylation in bronchial epithelial cells by CD-40-CD40L pathway Source: Eur Respir J 2002; 20: Suppl. 38, 573s Year: 2002
N-acetylcysteine reduces chemokine release via inhibition of p38 MAPK in human airway smooth muscle cells Source: Eur Respir J 2003; 22: 43-49 Year: 2003
Increased expression of p38 MAPK in human bronchial epithelium after lipopolysaccharide exposure Source: Eur Respir J 2005; 25: 797-803 Year: 2005
Exogenous HSP60 stimulates airway smooth muscle cell remodeling via MAPK p38 pathway Source: Virtual Congress 2020 – Monitoring of inflammation in remodelling Year: 2020
Syk is downstream of ICAM-1 and mediates human rhinovirus (HRV) activation of p38 MAP kinase in airway epithelial cells Source: Annual Congress 2006 - Airway epithelial cells in inflammation Year: 2006
Inhibition of VEGF blocks the activation of TGF-β1 through a PI3K/Akt signaling pathway in allergic airway disease of mice Source: Annual Congress 2007 - Current issues in airway physiology, pharmacology and monitoring Year: 2007
Inhibition of GM-CSF generation in human alveolar macrophages by reduction of histone acetylation and by dephosphorylation of p38 MAPK and MKK-1 Source: Eur Respir J 2001; 18: Suppl. 33, 475s Year: 2001
N-Acetylcysteine inhibits eotaxin and MCP-1 release in human airway smooth muscle cells in vitro through the inhibition of ROS production, resulting in a decrease of p38 MAP kinase activation Source: Eur Respir J 2002; 20: Suppl. 38, 170s Year: 2002
Inhibition of P38 kinase does not reduce production of TNF-alpha from airway cells in COPD Source: Annual Congress 2007 - Epithelial networks in the airways Year: 2007
Exposure to LPS induces the upregulation of p38 MAPK in human bronchial epithelium in vivo Source: Eur Respir J 2003; 22: Suppl. 45, 459s Year: 2003
P38 MAPK and MMP-9 mediate airway mucus hypersecretion induced by acrolein Source: Annual Congress 2007 - Recent advances in our understanding of the mechanisms of asthma treatment Year: 2007
Role of dexamethasone and MAPkinases ERK and p38MAPK on T-bet expression and IFNγ release in peripheral blood lymphocytes from atopic asthmatics Source: Eur Respir J 2006; 28: Suppl. 50, 229s Year: 2006
Effect of p38 MAPK inhibition on corticosteroid suppression of cytokine release in severe asthma Source: Eur Respir J 2010; 35: 750-756 Year: 2010
Apoptosis signal-regulating kinase 1 regulates leukotirene D4-induced AP-1 activation in human airway smooth muscle cells Source: Eur Respir J 2004; 24: Suppl. 48, 37s Year: 2004
Effects of budesonide on p38 MAPK activation, apoptosis and IL-8 secretion, induced by TNF-alpha and Haemophilus influenzae in human bronchial epithelial cells Source: Annual Congress 2010 - Regulation of airway pharmacology Year: 2010
Inhibition of p38 MAPK-dependent bronchial contraction after ozone by corticosteroids Source: Eur Respir J 2011; 37: 933-942 Year: 2011
The p38 MAP kinase inhibitor dilmapimod ameliorates airway inflammation induced by ozone challenge in healthy volunteers Source: Annual Congress 2012 - Treatment of asthma, bronchiectasis and cough: inhaler use Year: 2012