Decreased PTEN amplifies PI3K signaling and enhances pro-inflammatory cytokine release in COPD Source: International Congress 2016 – Studies in airway cell biology Year: 2016
Neutrophil elastase causes MUC5AC mucin synthesis via a EGF receptor, ERK and NF-kB pathway in A549 cells Source: Eur Respir J 2004; 24: Suppl. 48, 554s Year: 2004
Vitamin E down-modulates activation of NFκB, secretion of IL-8 and expression of cell adhesion molecules in lung epithelial cells Source: Eur Respir J 2002; 20: Suppl. 38, 620s Year: 2002
Prostaglandin E2 inhibits NLRP3 inflammasome activation through EP4 receptor and intracellular cAMP in human macrophages Source: International Congress 2015 – Mucosal immunology: what’s new in 2015 Year: 2015
Inhibitory effects of the IL-6 receptor superantagonist SANT7 on MAP kinase phosphorylation and cell proliferation induced by IL-6 and TGF-beta1 in human lung fibroblasts Source: Annual Congress 2008 - Clinical aspects of interstitial lung disease Year: 2008
Endotoxin induces proliferation of NSCLC cells by a COX-2 dependent manner – Role of CD14, TLRs and EGFR signaling Source: Annual Congress 2010 - Pathology of lung cancer Year: 2010
Proteinase-activated receptor-2 (PAR2 ) activation on human lung fibroblasts increases IL-6 & IL-8 mRNA expression Source: Annual Congress 2003 - Mechanisms of lung injury: from bench to bedside Year: 2003
Bile acid receptor accelerates to the lung cancer process induced by lung fibroblast-tumor cells interaction, with high activation of phosphorylated STAT3 and alteration of cytokine secretion Source: International Congress 2017 – Lung cancer - basic science: the latest results from the bench Year: 2017
Stimulation of NOD1 induces RIP2, TAK1 and p38 MAPK dependent pro-inflammatory signalling in human lung microvascular endothelial cells Source: Annual Congress 2011 - Mechanisms of acute lung injury and mesenchymal cell treatment Year: 2011
Glucocorticoids promote TGF-β signalling in lung fibroblasts by upregulating ligand and receptor expression, and uncoupling negative-feedback inhibition Source: Annual Congress 2010 - Recent developments of molecular pathology and functional genomics in non-neoplastic and neoplastic lung diseases Year: 2010
Effects of endothelin-1 on MAPK activation, IL-6 production and cell proliferation in normal human lung fibroblasts Source: Eur Respir J 2004; 24: Suppl. 48, 454s Year: 2004
Thrombin induces stomatin-like protein 2 (STOML2) expression and IL-8/CXCL8 release by ROCK, JNK, and PEA3 pathways in human lung epithelial cells Source: Virtual Congress 2020 – Asthma science: novel targets and mechanisms Year: 2020
GB001 potently inhibits PGD2 metabolite-induced DP2-mediated cell signaling and eosinophil activation Source: Virtual Congress 2020 – Asthma science: novel targets and mechanisms Year: 2020
Leptin activates the JAK/STAT signaling pathway in bronchial and alveolar epithelial cells Source: Eur Respir J 2006; 28: Suppl. 50, 338s Year: 2006
Inhibition of IRAK4 suppresses chemokine release from human bronchial epithelial cells Source: Annual Congress 2013 –Molecular biology: state-of-the-art 2013 Year: 2013
Effects of budesonide on p38 MAPK activation, apoptosis and IL-8 secretion, induced by TNF-alpha and Haemophilus influenzae in human bronchial epithelial cells Source: Annual Congress 2010 - Regulation of airway pharmacology Year: 2010
Endothelin-1 activates pro-inflammatory signalling pathway via destinct p38MAPK isoforms resulting in downregulation of nuclear p27kip1 Source: Annual Congress 2009 - Airway cell biology Year: 2009
Activation of IL-32 pathway in COPD Source: Annual Congress 2008 - Cell biology of asthma and COPD Year: 2008
Protein kinase C and mitochondrial signaling mediate PM10-induced ROS and TGF-β expression in the bronchial epithelial cells Source: Eur Respir J 2007; 30: Suppl. 51, 574s Year: 2007
Transforming growth factor-β inhibition of lung fibroblast proliferation is mediated through prostaglandin E2 , via activation of p38 mitogen-activated protein kinase Source: Annual Congress 2005 - Pulmonary hypertension and fibrosis: novel mechanisms Year: 2005