TLR4 signaling as a potentiator in the airway submucosal gland secretion

K. Murakami, T. Tamada, M. Nara, S. Muramatsu, T. Kikuchi, M. Kanehira, M. Ebina, T. Nukiwa (Sendai, Japan)

Source: Annual Congress 2010 - Lung cell biology and immunology
Session: Lung cell biology and immunology
Session type: Thematic Poster Session
Number: 2412
Disease area: Respiratory infections

Congress or journal article abstract

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
K. Murakami, T. Tamada, M. Nara, S. Muramatsu, T. Kikuchi, M. Kanehira, M. Ebina, T. Nukiwa (Sendai, Japan). TLR4 signaling as a potentiator in the airway submucosal gland secretion. Eur Respir J 2010; 36: Suppl. 54, 2412

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
TLR4 signaling potentiates airway secretion from the swine submucosal gland via NO/cGMP/cGK pathway
Source: Annual Congress 2012 - Cellular signalling mechanisms in the airways
Year: 2012

TLR4 mediates LPS-induced mucus hypersecretion in rat airway
Source: Annual Congress 2007 - Epithelial networks in the airways
Year: 2007


Activation of beta2-adrenoceptor signaling is required for IL-13 induced production of mucous metaplasia
Source: Annual Congress 2010 - Regulation of airway pharmacology
Year: 2010

Regulation of MUC5AC mucin secretion by depletion of AQP5 in human airway submucosal gland cells
Source: Eur Respir J 2006; 28: Suppl. 50, 756s
Year: 2006

Flagellin potentiates the Ca2+-dependent electrolytes secretion from airway submucosal gland in a TLR4-independent, TLR5-dependent and cGK-dependent manner
Source: Annual Congress 2012 - Cellular signalling mechanisms in the airways
Year: 2012

Neuropeptide regulation of secretion and inflammation in human airway gland serous cells
Source: Eur Respir J, 55 (4) 1901386; 10.1183/13993003.01386-2019
Year: 2020



Intranasal steroids decrease eosinophils but not mucin expression in nasal polyps
Source: Eur Respir J 2004; 24 : 594-600
Year: 2004



NOTCH-1 activation sustains hyperexpression of IL-33 in the epithelium of nasal polyps
Source: International Congress 2017 – Systemic and airway biomarkers
Year: 2017

Thrombin stimulates mucin secretion from airway epithelial cells
Source: Eur Respir J 2002; 20: Suppl. 38, 570s
Year: 2002

IP-10 decreases TNFα-induced mucin secretion in airway epithelial cell
Source: Eur Respir J 2006; 28: Suppl. 50, 827s
Year: 2006

Attenuated cytokine response and enhanced toll-like receptor expression by budesonide in bronchial epithelial cells
Source: Eur Respir J 2006; 28: Suppl. 50, 101s
Year: 2006

IL33 expression and release from airway epithelium
Source: Annual Congress 2012 - Cellular signalling mechanisms in the airways
Year: 2012

PPARγ agonists modulate transepithelial anion secretion in human airway epithelial cells
Source: Eur Respir J 2005; 26: Suppl. 49, 483s
Year: 2005

Muscarinic receptor subtypes in cilia-driven transport and airway epithelial development
Source: Eur Respir J 2009; 33: 1113-1121
Year: 2009



Effects of protease-activated receptor-2 stimulation on human and rodent airway mucus secretion
Source: Eur Respir J 2002; 20: Suppl. 38, 573s
Year: 2002

A potentiating effect of endogenous nitric oxide in the physiologic secretion from airway submucosal glands
Source: Annual Congress 2008 - Basic science in asthma and COPD
Year: 2008

AQP5 role in ovalbumin-induced airway inflammation and secretion of MUC5AC in mice
Source: Annual Congress 2011 - Animal models of airway inflammation
Year: 2011


Leptin activates the JAK/STAT signaling pathway in bronchial and alveolar epithelial cells
Source: Eur Respir J 2006; 28: Suppl. 50, 338s
Year: 2006

Analysis of signal transduction pathways involved in proteinase activated receptor-2 (PAR-2) stimulated mucus secretion in human tracheal gland cell culture
Source: Annual Congress 2008 - Airway cell biology
Year: 2008