N-acetylcysteine protects the rat diaphragm against the deleterious effects of mechanical ventilation

A. Agten, K. Maes, A. Smuder, S. Powers, M. Decramer, G. Gayan-Ramirez (Belgium; Gainesville, United States Of America)

Source: Annual Congress 2010 - Mechanical ventilation and weaning
Session: Mechanical ventilation and weaning
Session type: E-Communication Session
Number: 2226
Disease area: Respiratory critical care

Congress or journal article abstractE-poster

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
A. Agten, K. Maes, A. Smuder, S. Powers, M. Decramer, G. Gayan-Ramirez (Belgium; Gainesville, United States Of America). N-acetylcysteine protects the rat diaphragm against the deleterious effects of mechanical ventilation. Eur Respir J 2010; 36: Suppl. 54, 2226

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Corticosteroid treatment worsens the detrimental effect of mechanical ventilation on rat diaphragm function
Source: Eur Respir J 2002; 20: Suppl. 38, 222s
Year: 2002

Intermittent spontaneous breathing during the course of mechanical ventilation protects the rat diaphragm function from mechanical ventilation effects
Source: Annual Congress 2004 - Skeletal muscle in respiratory disease
Year: 2004


Rocuronium enhances detrimental effects of 24 hours mechanical ventilation on rat diaphragm function
Source: Eur Respir J 2004; 24: Suppl. 48, 266s
Year: 2004

High dose corticosteroids may protect the rat diaphragm from mechanical ventilation (MV) effects
Source: Eur Respir J 2005; 26: Suppl. 49, 88s
Year: 2005

Short-term mechanical ventilation induces oxidative stress and inflammation in healthy mouse lungs
Source: Annual Congress 2010 - New insights into reactive oxygen species
Year: 2010


High dose methylprednisolone counteracts the negative effect of rocuronium on diaphragm function in a rat model of mechanical ventilation
Source: Annual Congress 2011 - Mechanical ventilation and weaning
Year: 2011


Effects of rocuronium treatment during mechanical ventilation (MV) on rat diaphragm function
Source: Eur Respir J 2005; 26: Suppl. 49, 88s
Year: 2005

Can phrenic stimulation protect the diaphragm from mechanical ventilation-induced damage?
Source: Eur Respir J 2013; 42: 280-283
Year: 2013


Mechanical ventilation in humans elicits autophagy in the diaphragm
Source: Annual Congress 2009 - New data on respiratory function - from experimental approaches to man
Year: 2009


Protective effect of methylprednisolone on ventilator-induced diaphragm dysfunction is dose dependent
Source: Annual Congress 2009 - New results in molecular pathology and functional genomics of non-neoplastic lung diseases
Year: 2009

Effects of cold preservation on the lung respiratory mechanical properties of the rat
Source: Eur Respir J 2002; 20: Suppl. 38, 104s
Year: 2002

Prevention of hyperoxia-induced lung injury: Counterbalancing the deleterious effects of endothelin-1 in rat lungs
Source: Annual Congress 2012 - Lung injury and repair: reactive oxygen species and beyond
Year: 2012

Protective effects of hypercapnic acidosis on endotoxin-induced endothelial cell injury
Source: Eur Respir J 2004; 24: Suppl. 48, 721s
Year: 2004

Induction of antioxidant defense mechanisms by amifostine in lung tissue attenuates ventilator induced lung injury
Source: Annual Congress 2010 - New insights into reactive oxygen species
Year: 2010


Lung damage in chronic hypoxic rats and antagonistic effects of aminophylline on the damage
Source: Annual Congress 2008 - Pathophysiology of respiratory diseases
Year: 2008


Does hypercapnia and respiratory acidosis have protective effect in a ventilator-induced lung injury model?
Source: Eur Respir J 2005; 26: Suppl. 49, 559s
Year: 2005

Oral N-acetylcysteine affects chemically and mechanically-induced cough in guinea pig model of hyperoxia-induced oxidative stress
Source: Eur Respir J 2007; 30: Suppl. 51, 364s
Year: 2007

Effect of inhaled N-acetylcysteine on the oxidative stress and content of proteases in lungs of newborn guinea pigs exposed to hyperoxia
Source: International Congress 2018 – Molecular and cellular determinants of the developing lung
Year: 2018

Aminosteroidal and benzylisoquinoline NMBAs have different effects on the rat diaphragm during controlled mechanical ventilation (CMV)
Source: Annual Congress 2006 - Acute respiratory distress syndrome (ARDS): from pathophysiology to clinical management
Year: 2006


NMBAs exert different effects on calpain activity in the diaphragm during controlled mechanical ventilation (CMV)
Source: Eur Respir J 2007; 30: Suppl. 51, 52s
Year: 2007