PP216 – Glucocorticoids exacerbate TGFß1 mediated fibrotic signalling in lung fibroblasts by inhibition of metalloproteinase expression and activity Source: ERS Lung Science Conference 2021 Year: 2021
The PDE4-inhibitors roflumilast and rolipram modulate fibroblast collagen-gel contraction and chemotaxis mediated by autocrine PGE2 synthesis induced by TGF-β1 Source: Eur Respir J 2005; 26: Suppl. 49, 214s Year: 2005
Inhibition of HGF secretion by pulmonary fibroblasts from IPF: involvement of PGE2 Source: Eur Respir J 2003; 22: Suppl. 45, 8s Year: 2003
The inhibitory mechanism of transferring iNOS gene to PASMCs on hypoxia induced proliferation Source: Eur Respir J 2002; 20: Suppl. 38, 88s Year: 2002
Mechanisms of acetylcholine-induced release of proinflammatory extracellular vesicles by endothelial cells and inhibitory effects of tiotropium Source: International Congress 2019 – Identification of new targets and therapeutic strategies for lung disease Year: 2019
Synergistic action of formoterol on budesonide-generated decrease of proteoglycan production by activated lung fibroblasts is mediated via β-adrenergic receptor and is dependent on glucocorticoid receptor Source: Eur Respir J 2004; 24: Suppl. 48, 345s Year: 2004
Effects of endothelin-1 on MAPK activation, IL-6 production and cell proliferation in normal human lung fibroblasts Source: Eur Respir J 2004; 24: Suppl. 48, 454s Year: 2004
Glucocorticoids promote TGF-β signalling in lung fibroblasts by upregulating ligand and receptor expression, and uncoupling negative-feedback inhibition Source: Annual Congress 2010 - Recent developments of molecular pathology and functional genomics in non-neoplastic and neoplastic lung diseases Year: 2010
Differential role of EPAC and PKA in the transduction of cAMP-mediated inhibition of human lung fibroblast proliferation and collagen synthesis Source: Annual Congress 2009 - Pathological remodelling in chronic lung disease: from epithelial-mesenchymal transition to cellular activation Year: 2009
Autocrine secretion of bradykinin prevents alveolar type II cells from mechanical stretch-induced apoptosis by activation – role of PI3K and Akt Source: Annual Congress 2008 - Border patrol: the alveolar barrier in lung injury Year: 2008
Anti-inflammatory effect of bosentan on endothelin-1- and TNF-α-induced GMCSF expression in human airways smooth muscle cells – role of MAPkinases ERK-1,-2 Source: Annual Congress 2007 - Inflammatory cell biology Year: 2007
Inhibitory effect of statins on fibrogenic mediator production from lung cells Source: Annual Congress 2012 - Diffuse parenchymal lung disease pathogenesis, biomarkers, therapy and new entities Year: 2012
TNF-α and TGF-β1 synergistically upregulate the expression of endothelin-1 in airway epithelial cell Source: Annual Congress 2009 - Epithelial cell biology Year: 2009
In vitro profibrotic effects of rapamycin on basal or TGF-β1 induced primary human lung fibroblast: ECM production and turnover, migration and differentiation Source: Annual Congress 2012 - Diffuse parenchymal lung disease I Year: 2012
Prostaglandin-E2 mediated inhibition of TNFα release from human alveolar macrophages Source: Eur Respir J 2005; 26: Suppl. 49, 223s Year: 2005
Hypoxia impairs β2 adrenergic signalling and stimulation of alveolar reabsorption in rat alveolar epithelial cells Source: Annual Congress 2009 - Highlighting the epithelial cell in lung disease: from COPD to cancer to acute lung injury Year: 2009
Activation of TLR3 augments myofibroblasts differentiation and extracellular matrix production Source: Annual Congress 2009 - Lung cell biology and immunology Year: 2009
N-Acetylcysteine inhibits eotaxin and MCP-1 release in human airway smooth muscle cells in vitro through the inhibition of ROS production, resulting in a decrease of p38 MAP kinase activation Source: Eur Respir J 2002; 20: Suppl. 38, 170s Year: 2002
Effects of TGF-beta and budesonide on MAPK phosphorylation, IL-6/IL-11 secretion, and cell proliferation in human lung fibroblasts Source: Eur Respir J 2006; 28: Suppl. 50, 662s Year: 2006
Effect of in vivo blockade of the KCa3.1 ion channel on type II alveolar epithelial cell turnover in pulmonary fibrosis Source: International Congress 2018 – Novel insights in the basic and translational research on idiopathic interstitial pneumonias Year: 2018