VIP prevents and reverses monocrotaline-induced PAH: Further protection by combination with bosentan

S. Hamidi, A. Szema, R. Khatami, S. Said (Northport, United States Of America)

Source: Annual Congress 2010 - Experimental pulmonary hypertension
Session: Experimental pulmonary hypertension
Session type: Thematic Poster Session
Number: 1072
Disease area: Pulmonary vascular diseases

Congress or journal article abstractE-poster

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
S. Hamidi, A. Szema, R. Khatami, S. Said (Northport, United States Of America). VIP prevents and reverses monocrotaline-induced PAH: Further protection by combination with bosentan. Eur Respir J 2010; 36: Suppl. 54, 1072

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Fasudil reduces monocrotaline-induced pulmonary arterial hypertension: comparison with bosentan and sildenafil
Source: Eur Respir J 2010; 36: 800-807
Year: 2010



VIP greatly attenuates monocrotaline-induced pulmonary vasculopathy in rats
Source: Annual Congress 2009 - Pathobiology of pulmonary hypertension
Year: 2009



Effect of roflumilast on hypoxia- and monocrotaline-induced pulmonary hypertension in rats
Source: Annual Congress 2007 - Recent advances in the understanding of lung injury and repair
Year: 2007


ACE2 activation improves pulmonary endothelial function and attenuates monocrotaline-induced pulmonary hypertension
Source: Annual Congress 2011 - Treatment of human pulmonary hypertension
Year: 2011


Optimization of tissue targeting properties of macitentan, a new dual endothelin receptor antagonist, improves its efficacy in a rat model of pulmonary fibrosis associated with pulmonary arterial hypertension
Source: Annual Congress 2011 - Treatment of human pulmonary hypertension
Year: 2011


2-Methoxyestrone inhibits vascular remodeling and attenuates monocrotaline-induced pulmonary hypertension
Source: Annual Congress 2008 - Pulmonary vascular biology
Year: 2008

Sildenafil enhances the pulmonary vasodilatory response to inhaled iloprost in experimental pulmonary hypertension
Source: Eur Respir J 2002; 20: Suppl. 38, 24s
Year: 2002

A prostacyclin analogue, iloprost, protects from bleomycin-induced pulmonary fibrosis in mice
Source: Annual Congress 2010 - Experimental approaches in pulmonary fibrosis
Year: 2010

2-Ethoxyestradiol inhibits vascular and cardiac remodeling and attenuates monocrotaline-induced pulmonary hypertension
Source: Annual Congress 2007 - Cellular and molecular aspects of pulmonary hypertension
Year: 2007


Successful transition from oral prostacyclin analogue (beraprost) to the selective endothelin receptor antagonist (sitaxsentan) therapy in pulmonary arterial hypertension
Source: Annual Congress 2007 - Pulmonary hypertension: diagnosis and treatment
Year: 2007



Combination therapy with bosentan and sildenafil in idiopathic pulmonary arterial hypertension
Source: Eur Respir J 2004; 24: 1007-1010
Year: 2004



Treatment effects of Rho-kinase (Rock) inhibition vs. phosphodiesterase-5 (PDE5) inhibition on cardiac function and metabolism in monocrotaline induced pulmonary arterial hypertension
Source: Eur Respir J 2006; 28: Suppl. 50, 547s
Year: 2006

Prevention and partial reversal of monocrotaline-induced pulmonary arterial hypertension (PAH) by hsp90 inhibitors
Source: Annual Congress 2012 - Pulmonary circulation: basic mechanisms, animal models and experimental treatments
Year: 2012

Hypoxia-induced pulmonary hypertension: Synergistic effects of sildenafil and erythropoietin in mice
Source: Annual Congress 2012 - Pulmonary circulation: basic mechanisms, animal models and cell biology
Year: 2012


Roflumilast N- oxide combined with sildenafil reverses cellular remodeling on IPF models
Source: International Congress 2017 – Towards new anti-inflammatory and anti-fibrotic agents
Year: 2017



Additive protective effects of sacubitril/valsartan and bosentan on vascular remodeling in experimental pulmonary hypertension
Source: Virtual Congress 2020 – Experimental approaches to pulmonary hypertension
Year: 2020


Esterification of iloprost enhances its protective effects on pulmonary endothelium
Source: Respiratory Failure and Mechanical Ventilation Conference 2020
Year: 2020



Dual endothelin-1 receptor antagonism prevents chronic intermittent hypoxia-induced cardiovascular alterations in rats
Source: Annual Congress 2008 - Innovative treatments in sleep disordered breathing
Year: 2008

Oestradiol ameliorates monocrotaline pulmonary hypertension via NO, prostacyclin and endothelin-1 pathways
Source: Eur Respir J 2013; 41: 1116-1125
Year: 2013



Genistein rescues pulmonary hypertension and attenuates abnormal vasoconstriction in rats lungs
Source: Annual Congress 2012 - Pulmonary circulation: basic mechanisms, animal models and experimental treatments
Year: 2012