Suplatast tosilate decreases goblet cell metaplasia in patients with asthma

M. Hoshino, T. Nakagawa, T. Miyazawa (Kawasaki, Japan)

Source: Annual Congress 2006 - Established and experimental therapies for allergic asthma
Session: Established and experimental therapies for allergic asthma
Session type: Thematic Poster Session
Number: 2554
Disease area: Airway diseases

Congress or journal article abstract

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
M. Hoshino, T. Nakagawa, T. Miyazawa (Kawasaki, Japan). Suplatast tosilate decreases goblet cell metaplasia in patients with asthma. Eur Respir J 2006; 28: Suppl. 50, 2554

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
A comparison of suplatast tosilate, a Th2 cytokine inhibitor, and inhaled fluticasone propionate for airway inflammation in mild asthma
Source: Eur Respir J 2002; 20: Suppl. 38, 373s
Year: 2002

Inhibition of neutrophil elastase-induced goblet cell metaplasia by tiotropium in mice
Source: Eur Respir J 2010; 35: 1164-1171
Year: 2010



Tiotropium inhibits airway inflammation and goblet cell metaplasia in a model of relapsing asthma in mice
Source: International Congress 2015 – Animal studies of asthma and other inflammatory conditions
Year: 2015

CC chemokine receptor 3 inhibitor, antileukinate, suppressed ovalbumin induced goblet cell metaplasia and airway hyperresponsiveness in mice
Source: Annual Congress 2005 - Basic mechanisms in asthma and COPD: new insights
Year: 2005


Therapeutic effect of roflumilast on LPS- and OVA-induced goblet cell hyperplasia in rats
Source: Eur Respir J 2007; 30: Suppl. 51, 25s
Year: 2007

Effect of verapamil on bronchial goblet cells of asthma
Source: Annual Congress 2010 - Models of airways disease
Year: 2010


Recruitment of eosinophils and increased expression of mast cells tryptase in the bronchial mucosa of patients with allergic asthma
Source: Eur Respir J 2002; 20: Suppl. 38, 508s
Year: 2002

The influence of smoking on the formation of cold airway hyperresponsiveness and destructive-cytolytic profile of goblet cells in asthma patients
Source: International Congress 2018 – Studying novel biomarkers in asthma and COPD
Year: 2018


Relationship between allergen-induced increase of AHR to bradykinin, expression of the proliferation marker Ki-67 and eosinophils in bronchial mucosa of atopic asthmatics
Source: Annual Congress 2003 - Modulation of bronchial hyperreactivity and immune response in the airways
Year: 2003


Change of secretory activity of goblet cells of bronchial epithelium in asthma patients in response to cold airway challenge
Source: International Congress 2018 – COPD: novel pathological mechanisms in the airway epithelium
Year: 2018


Tiotropium and fluticasone inhibit rhinovirus-induced mucin production via multiple mechanisms in differentiated airway epithelial cells
Source: Virtual Congress 2020 – Host-microbe interactions and their influence on lung disease onset and severity
Year: 2020


Failure of montelukast to reduce sputum eosinophilia in high-dose corticosteroid-dependent asthma
Source: Eur Respir J 2005; 25: 41-46
Year: 2005



Increased expression of IL-19 in metaplastic epithelium of patients with chronic rhinosinusitis and nasal polyps
Source: Annual Congress 2011 - Epithelial cell biology
Year: 2011

Association between eosinophilic airway inflammation and T-cells response in children with bronchial asthma
Source: Annual Congress 2010 - Mechanisms and modulation of allergic inflammation in the lung
Year: 2010


Influence of large and small dose of fluticasone propionate on clinical symptoms of bronchial asthma, lung function, bronchial hyperreactivity and eosinophilia in induced sputum
Source: Eur Respir J 2002; 20: Suppl. 38, 111s
Year: 2002

Inflammatory cell counts in induced sputum from non-allergic asthmatics and COPD patients
Source: Eur Respir J 2004; 24: Suppl. 48, 317s
Year: 2004

Fluticasone propionate decreases MUC5AC expression on airway epithelial cells induced by rhinovirus infection in the airway
Source: Annual Congress 2011 - Experimental modulation of airway inflammation
Year: 2011

Differential treatment response to mepolizumab in severe eosinophilic asthma with nasal polyps
Source: Virtual Congress 2020 – Monoclonal antibodies in asthma
Year: 2020


Sputum mast cell subtypes relate to eosinophilia and corticosteroid response in asthma
Source: Eur Respir J 2016; 47: 1123-1133
Year: 2016



Eotaxins expression in nasal mucosa in patients with asthma and seasonal rhinitis
Source: Annual Congress 2010 - Cell biology and immunology of lung disease
Year: 2010