ST2 gene knockout attenuates allergic airways disease

P. Kewin, D. Xu, M. Patel, B. Choo-Kang, N. Pitman, N. C. Thomson, F. Y. Liew (Glasgow, United Kingdom)

Source: Annual Congress 2006 - Immunological mechanisms in cell recruitment to the lungs
Session: Immunological mechanisms in cell recruitment to the lungs
Session type: Oral Presentation
Number: 1739
Disease area: Airway diseases

Congress or journal article abstractSlide presentation

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
P. Kewin, D. Xu, M. Patel, B. Choo-Kang, N. Pitman, N. C. Thomson, F. Y. Liew (Glasgow, United Kingdom). ST2 gene knockout attenuates allergic airways disease. Eur Respir J 2006; 28: Suppl. 50, 1739

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Deficiency of MMP-19 promotes allergen-induced eosinophil burden and airway responsiveness in mice
Source: Annual Congress 2007 - Regulation of allergic airway inflammation in animal models of asthma
Year: 2007



Local application of FTY720 to the lung abrogates experimental asthma by altering myeloid dendritic cell function
Source: Annual Congress 2006 - Towards understanding the pathogenesis of asthma
Year: 2006


IL-13-dependent C3a-release in a murine model of allergic asthma
Source: Annual Congress 2005 - Airway epithelial cells in asthma and COPD
Year: 2005


Murine models of asthma
Source: Eur Respir J 2003; 22: 374-382
Year: 2003



The development of an airway hyperresponsiveness (AHR) depends on mast cells following sensitization without adjuvant
Source: Annual Congress 2006 - Cellular immunology in asthma pathogenesis
Year: 2006


Models of asthma employing ovalbumin in rats and mice: similarities and differences compared with patient asthma
Source: Annual Congress 2005 - PG11 - Experimental models for COPD and asthma
Year: 2005


Bronchial inflammatory changes in wheezy infants
Source: Annual Congress 2007 - Bronchial inflammation in wheezing infants and pre-school children
Year: 2007


MMP-9 deficiency reduces airway inflammation and hyperresponsiveness in a mouse model of asthma
Source: Eur Respir J 2001; 18: Suppl. 33, 20s
Year: 2001

Effects of IL-4Rα blockade on lung inflammation and airway hyperresponsiveness using Mu317RAXMu, a murine surrogate for AMG 317, in a treatment model of cockroach allergen-induced asthma in mice
Source: Annual Congress 2008 - Novel mechanisms in the pathogenesis of pulmonary inflammation
Year: 2008

Experimental specific immunotherapy with timpol decreases allergic sensitization and airway inflammation in murine model of bronchial asthma
Source: Annual Congress 2010 - Animal models of asthma and lung inflammation
Year: 2010


Plasma cells in the airways express neurotrophins and neurotrophin-receptors in a mouse model of chronic allergic asthma
Source: Annual Congress 2007 - Regulation of allergic airway inflammation in animal models of asthma
Year: 2007


CCL6 produced by eosinophils drives allergic airway inflammation in mice
Source: International Congress 2019 – Modelling and monitoring of airway diseases
Year: 2019

Opioid-neurotensin hybrid influences pulmonary inflammatory process in murine model of non-atopic asthma.
Source: International Congress 2017 – Towards better treatments for lung disease: experimental pharmacology
Year: 2017

Improving of experimental allergic asthma by decreased Th2 responses in OGR-1 knockout mice
Source: Annual Congress 2010 - Animal models of asthma and lung inflammation
Year: 2010


Effects of OVA-induced allergic airway inflammation and remodeling in mice in three distinct asthma models
Source: Annual Congress 2010 - Animal models of asthma and lung inflammation
Year: 2010


Overexpression of eNOS suppresses asthmatic features in a mouse model of allergic asthma
Source: Eur Respir J 2002; 20: Suppl. 38, 28s
Year: 2002

PDE-4-inhibitor rolipram supports treg-mediated suppression in a murine model of allergic airway disease
Source: Annual Congress 2008 - Risk factors for asthma versus asthma control
Year: 2008

Decreased Smad7 expression in the airways of a mouse model of chronic asthma
Source: Annual Congress 2004 - Animal models of allergic airway disease
Year: 2004


Treatment with Syk inhibitors after establishment of disease phenotype in a chronic HDM model of allergic airways inflammation abolishes AHR and attenuates inflammatory mediator expression
Source: International Congress 2015 – New targets and modalities for the treatment of asthma and COPD
Year: 2015

Oophorectomy decreases airway responsiveness but not eosinophilia in an ovalbumin sensitization murine model of allergy
Source: Annual Congress 2006 - Cell biology of asthma and COPD
Year: 2006