Phosphoinositide 3-kinase ? inhibitor suppresses interleukin-17 expression in a murine asthma model Source: Eur Respir J 2010; 36: 1448-1459 Year: 2010
The pan janus kinase (JAK) inhibitor KN-002 suppresses inflammatory mediator release from severe asthma bronchial epithelial cells. Source: Virtual Congress 2021 – Airway pharmacology: translational and basic science Year: 2021
The effect of smoking on phosphoinositide 3-kinase (PI3K) and phosphatase and tensin homolog deleted from chromosome 10 (PTEN) mRNA expression in human airway epithelial cells Source: International Congress 2014 – Mechanistic studies of the airway epithelium Year: 2014
Activation of second messenger pathways in alveolar macrophages by endotoxin Source: Eur Respir J 2002; 20: 210-222 Year: 2002
Inhibition of P38 kinase does not reduce production of TNF-alpha from airway cells in COPD Source: Annual Congress 2007 - Epithelial networks in the airways Year: 2007
Gene transfer of a β-adrenergic receptor kinase inhibitor up-regulated levels of β-adrenergic receptor and cAMP in asthmatic murine lung Source: Eur Respir J 2005; 26: Suppl. 49, 580s Year: 2005
A phosphatidylinositol 3-kinase Inhibitor strongly suppressed pulmonary vascular remodeling in a murine model of allergic vasculitis Source: International Congress 2015 – Animal studies of asthma and other inflammatory conditions Year: 2015
Phosphatidylinositol 3-kinase signaling is required for the differentiation of naive cells to CD103(αE β7 )+ /CD4+ -T-lymphocytes Source: Eur Respir J 2004; 24: Suppl. 48, 38s Year: 2004
RV568, a narrow-spectrum kinase inhibitor with p38 MAPK-a and -? selectivity, suppresses COPD inflammation Source: Eur Respir J, 50 (4) 1700188; 10.1183/13993003.00188-2017 Year: 2017
Effects of budesonide on p38 MAPK activation, apoptosis and IL-8 secretion, induced by TNF-alpha and Haemophilus influenzae in human bronchial epithelial cells Source: Annual Congress 2010 - Regulation of airway pharmacology Year: 2010
Differential actions of phosphatidyinositol 3-kinase inhibitors on respiratory burst and leukotriene C4 generation in PAF-stimulated human eosinophils Source: Eur Respir J 2003; 22: Suppl. 45, 547s Year: 2003
Inhibition of the glycogen synthase kinase 3β reduces steroid function in human monocytes Source: Annual Congress 2010 - Regulation of airway pharmacology Year: 2010
Regulation of cytokine- and phorbol ester-mediated interleukin (IL)-8 expression in the absence or presence of pyocyanin in human bronchial epithelial cell line: roles of protein kinase C and mitogen-activated protein kinases Source: Eur Respir J 2005; 26: Suppl. 49, 99s Year: 2005
Inhibition of VEGF blocks the activation of TGF-β1 through a PI3K/Akt signaling pathway in allergic airway disease of mice Source: Annual Congress 2007 - Current issues in airway physiology, pharmacology and monitoring Year: 2007
Regulation and overexpression of 85-kDa cytosolic phospholipase A2 in asthma Source: Annual Congress 2010 - New mechanisms in lung development, acute and chronic lung diseases Year: 2010
LATE-BREAKING ABSTRACT: Evaluation of an oral p38 mitogen activated protein kinase (MAPK inhibitor) SB-681323 in COPD Source: Annual Congress 2009 - COPD: from biomarker profiling to clinical assessment Year: 2009
Group V phospholipase A2 (gVPLA2 ) -induced eosinophil synthesis of LTC4 is independent of mitogen-activated protein kinases (MAPK) activation Source: Eur Respir J 2001; 18: Suppl. 33, 408s Year: 2001
C/EBP-β expression in mesothelioma cells is regulated by mitogen activated protein kinase p38-β and –gamma Source: Annual Congress 2009 - Lung cancer biology Year: 2009
Endothelin-1 activates pro-inflammatory signalling pathway via destinct p38MAPK isoforms resulting in downregulation of nuclear p27kip1 Source: Annual Congress 2009 - Airway cell biology Year: 2009
Inhibition of glycogen synthase kinase 3beta reduces GC function in human monocytes via modulation of HDAC2 activity Source: Annual Congress 2011 - Models of disease and drug actions Year: 2011