Modulation of vascular progenitor cell differentiation by TGFß and endothelin-1 receptor inhibition

M. Diez, M. M. Musri, E. Ferrer, S. Pizarro, J. A. Barbera, V. I. Peinado (Barcelona, Spain)

Source: Annual Congress 2009 - Pathobiology of pulmonary vascular diseases
Session: Pathobiology of pulmonary vascular diseases
Session type: E-Communication Session
Number: 4331
Disease area: Pulmonary vascular diseases

Congress or journal article abstractE-poster

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
M. Diez, M. M. Musri, E. Ferrer, S. Pizarro, J. A. Barbera, V. I. Peinado (Barcelona, Spain). Modulation of vascular progenitor cell differentiation by TGFß and endothelin-1 receptor inhibition. Eur Respir J 2009; 34: Suppl. 53, 4331

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

PEINADO Victor I. - 15.09.2009 10:52
Good work
This is an excellent work. Congratulations Marta! VIP
You must Login to comment this presentation.


Related content which might interest you:
Effect of endothelin-1 on migration of endothelial progenitor cells in vitro
Source: Annual Congress 2008 - Regulatory mechanisms of cell activation, renewal and recruitment
Year: 2008

Endothelin-1 induces calcium mobilisation but does not contribute to migration of endothelial progenitor cells in vitro
Source: Annual Congress 2009 - Mechanisms of lung injury: COPD, asthma and acute lung injury
Year: 2009


Bradykinin-induced fibroblast proliferation and myofibroblast differentiation via B2 receptor pathway
Source: Eur Respir J 2005; 26: Suppl. 49, 342s
Year: 2005

Endothelin and endothelial progenitor cells: a novel link in vasculogenesis
Source: Eur Respir J 2005; 26: Suppl. 49, 225s
Year: 2005

Profibrotic cytokine TGF-β1 increases endothelial progenitor cell angiogenic properties
Source: Annual Congress 2012 - Pulmonary circulation: basic mechanisms, animal models and experimental treatments
Year: 2012

Cell cooperation between human fibrocytes and endothelial progenitor cells during neoangiogenesis is driven by the CXCR4 pathway
Source: Annual Congress 2012 - Pulmonary circulation: basic mechanisms, animal models and cell biology
Year: 2012

Selective inhibition of COX-2 by celecoxib exerts negative effects on endothelial progenitor cell proliferation and stimulates apoptosis in vitro
Source: Eur Respir J 2005; 26: Suppl. 49, 368s
Year: 2005

Stimulation of pulmonary smooth muscle cell proliferation by endothelial progenitor cells
Source: Annual Congress 2008 - Vascular and interstitial remodelling in chronic lung disease: therapeutic interventions on the horizon
Year: 2008

Sildenafil modulates PDGF and Angiotensin II induced migration and proliferation in human pulmonary artery smooth muscle cells (PA-SMC)
Source: Eur Respir J 2002; 20: Suppl. 38, 227s
Year: 2002

Treprostinil indirectly regulates endothelial colony forming cell angiogenic properties by increasing VEGF-A produced by mesenchymal stem cells
Source: International Congress 2015 – Pulmonary hypertension: promising small molecules
Year: 2015

Effect of dexamethasone on TNFα-induced expression of vascular endothelial growth factor (VEGF) in human airway smooth muscle cells - role of histone-acetylation
Source: Eur Respir J 2004; 24: Suppl. 48, 695s
Year: 2004

TNF-α and TGF-β1 synergistically upregulate the expression of endothelin-1 in airway epithelial cell
Source: Annual Congress 2009 - Epithelial cell biology
Year: 2009

RB2/p130 gene-enhanced expression downregulates vascular endothelial growth factor expression and inhibits angiogenesis in vivo
Source: Eur Respir J 2002; 20: Suppl. 38, 3s
Year: 2002

Post-COVID-19 patients show an increased endothelial progenitor cell production
Source: Virtual Congress 2021 – Insights into pulmonary embolism
Year: 2021



The inducible kinin B1 receptor stimulates human airway fibroblast (Fb) proliferation
Source: Eur Respir J 2004; 24: Suppl. 48, 37s
Year: 2004

Caveolin-1 regulation of thrombin signalling in endothelial cells
Source: Annual Congress 2009 - Acute lung injury: biological mechanisms
Year: 2009


Glucocorticoids promote TGF-β signalling in lung fibroblasts by upregulating ligand and receptor expression, and uncoupling negative-feedback inhibition
Source: Annual Congress 2010 - Recent developments of molecular pathology and functional genomics in non-neoplastic and neoplastic lung diseases
Year: 2010

Modulating progenitor accumulation attenuates lung angiogenesis in a mouse model of asthma
Source: Eur Respir J 2011; 38: 679-687
Year: 2011



Down-regulation of the P2Y12 purinergic receptor expression on human bronchial epithelial cells by transforming growth factor-beta
Source: Annual Congress 2013 –Cell signalling and inflammation: what's new in 2013?
Year: 2013

Vascular endothelial growth factor induction by PGE2 in human airway smooth muscle cells is mediated by EP2/EP4 receptors and Sp-1 transcription factor binding sites
Source: Eur Respir J 2005; 26: Suppl. 49, 127s
Year: 2005