Procollagen I synthesis induced by TGFβ1 in bronchial biopsy fibroblasts from mild asthma patients is decreased by the budesonide/formoterol combination treatment

L. Todorova, L. Bjermer, A. Miller-Larsson, G. Westergren-Thorsson (Lund, Sweden)

Source: Annual Congress 2009 - Translational research/biomarkers
Session: Translational research/biomarkers
Session type: E-Communication Session
Number: 2926
Disease area: Airway diseases

Congress or journal article abstractE-poster

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
L. Todorova, L. Bjermer, A. Miller-Larsson, G. Westergren-Thorsson (Lund, Sweden). Procollagen I synthesis induced by TGFβ1 in bronchial biopsy fibroblasts from mild asthma patients is decreased by the budesonide/formoterol combination treatment. Eur Respir J 2009; 34: Suppl. 53, 2926

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Inhibitory effects of budesonide/formoterol on extracellular matrix in TGFß1-stimulated bronchial biopsy fibroblasts from mild asthmatic patients
Source: Annual Congress 2008 - Recent advances in the treatment and pathogenesis of asthma
Year: 2008

Inhibitory effects of budesonide and formoterol in combination on TGFβ-induced proteoglycan production by bronchial biopsy fibroblasts from healthy and mild asthmatic subjects
Source: Eur Respir J 2007; 30: Suppl. 51, 352s
Year: 2007

Treatment with inhaled steroids in patients with symptoms suggestive of asthma but with normal lung function
Source: Eur Respir J 2008; 32: 989-996
Year: 2008



Effects of regular formoterol treatment on airway hyperresponsiveness in patients with mild to moderate asthma
Source: Eur Respir J 2003; 22: Suppl. 45, 285s
Year: 2003

Effect of switching from high-dose inhaled corticosteroid (ICS) to low-dose ICS plus an inhaled long-acting β2-agonist on asthma control, airway inflammation and remodeling, and gene expression in airway epithelial cells
Source: Eur Respir J 2003; 22: Suppl. 45, 35s
Year: 2003

Salmeterol treatment improves corticosteroid responsivness in patients with corticosteroid-insensitive severe asthma
Source: Annual Congress 2005 - Improving asthma control in the harder-to-reach population
Year: 2005


Role of Pgp in corticosteroid sensitivity in patients with severe forms of bronchial asthma
Source: Annual Congress 2008 - Recent advances in the treatment and pathogenesis of asthma
Year: 2008


Stable COPD: predicting benefit from high-dose inhaled corticosteroid treatment
Source: Eur Respir J 2006; 27: 964-971
Year: 2006



Transbronchial fibroblasts from mild asthmatics have different proteoglycan production and migratory properties compared to transbronchial fibroblasts from rhinitis patients
Source: Annual Congress 2007 - Molecular pathogenesis: focus on COPD and asthma
Year: 2007


Efficacy of symbicort administration in patients with bronchial asthma
Source: Annual Congress 2009 - Treatment of airways disease
Year: 2009


Inhaled budesonide induces corticosteroid-dependent gene expression in asthmatics: Validation in primary epithelial and airways smooth muscle cells
Source: Annual Congress 2011 - Models of disease and drug actions
Year: 2011


Symptoms, induced sputum eosinophil percentages and treatment with salmeterol or fluticasone in mild asthmatics
Source: Eur Respir J 2001; 18: Suppl. 33, 336s
Year: 2001

Combined treatment with fluticasone plus salmeterol protects against allergen induced asthmatic responses and subsequent increase in sputum eosinophils
Source: Eur Respir J 2002; 20: Suppl. 38, 189s
Year: 2002

The importance of early applying inhaled corticosteroids in patients with mild bronchial asthma
Source: Eur Respir J 2002; 20: Suppl. 38, 57s
Year: 2002

Monitoring of inflammatory changes in patients with bronchial asthma before and after oral corticosteroid treatment
Source: Annual Congress 2008 - Novel experimental approaches to understanding asthma and COPD II
Year: 2008


Effects of formoterol-budesonide combination on residual eosinophilic inflammation in distal airway of patients with well-controlled moderate asthma
Source: Annual Congress 2011 - Asthma management and response
Year: 2011

Effect of inhaled budesonide on BAL inflammatory cells and MMP-12 expression in COPD
Source: Eur Respir J 2007; 30: Suppl. 51, 611s
Year: 2007

Steroid-resistant inflammation in a mouse model of severe asthma is not inhibited by the combination of theophylline and budesonide
Source: International Congress 2018 – Basic pharmacology
Year: 2018

The evaluation of bone density in the patients with bronchial asthma treated with glucocorticosteroids
Source: Eur Respir J 2002; 20: Suppl. 38, 51s
Year: 2002

Cytokines concentrations in induced sputum of mild COPD patients. Correlation to clinical response to inhaled corticosteroids
Source: Eur Respir J 2002; 20: Suppl. 38, 309s
Year: 2002