IL-13 enhances GSNO reductase activity and decreases intracellular S-nitrosothiols in lung epithelial cells

H. W. Shin, N. Malavia, E. M. Henderson, B. M. Gaston, S. C. George (Irvine, Charlottesville, United States Of America)

Source: Annual Congress 2006 - Airway cell biology II
Session: Airway cell biology II
Session type: E-Posters in free access
Number: 684
Disease area: Airway diseases

Congress or journal article abstract

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
H. W. Shin, N. Malavia, E. M. Henderson, B. M. Gaston, S. C. George (Irvine, Charlottesville, United States Of America). IL-13 enhances GSNO reductase activity and decreases intracellular S-nitrosothiols in lung epithelial cells. Eur Respir J 2006; 28: Suppl. 50, 684

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Curcumin induces glutathione biosynthesis and inhibits NF-κB activation and interleukin-8 release in alveolar epithelial cells
Source: Eur Respir J 2004; 24: Suppl. 48, 29s
Year: 2004

Xanthine oxidase inhibitors reduce rhinovirus induced IL-8 and GRO-α production in bronchial epithelial cells
Source: Eur Respir J 2007; 30: Suppl. 51, 721s
Year: 2007

IL-13 induces glucocorticoid resistance in iNOS expression and activity in human airway epithelial cells (HAECs)
Source: International Congress 2017 – New insights into pathogenesis of lung disease 
Year: 2017


N-acetyl cysteine inhibits IL-17-induced IL-8 production from human airway smooth muscle cells - a possible role for anti-oxidant treatment in chronic lung rejection?
Source: Eur Respir J 2003; 22: Suppl. 45, 202s
Year: 2003

Involvement of human bronchial epithelial cells in proliferation control of T-cells via reversible STAT5 dephosphorylation mediated by nitric oxide (NO)
Source: Eur Respir J 2002; 20: Suppl. 38, 207s
Year: 2002

The oxygen free radical-scavenger glutathione prevents the depletion of IL-16 in human CD8 lymphocytes that is caused by tobacco-smoke components in vitro
Source: Annual Congress 2007 - Inflammatory cell biology
Year: 2007


NF-κB-dependent cytokine production is abolished by cyclopentenone prostaglandins in lung epithelial cells
Source: Eur Respir J 2001; 18: Suppl. 33, 354s
Year: 2001

The intracellular thioredoxin system mediates inflammatory activation of human lung microvascular endothelial cells
Source: Eur Respir J 2003; 22: Suppl. 45, 223s
Year: 2003

Curcumin restores glucocorticoid function and inhibits cigarette smoke-mediated IL-8 release in oxidant stressed monocytic U937 cells
Source: Eur Respir J 2005; 26: Suppl. 49, 215s
Year: 2005

N-Acetylcysteine inhibits eotaxin and MCP-1 release in human airway smooth muscle cells in vitro through the inhibition of ROS production, resulting in a decrease of p38 MAP kinase activation
Source: Eur Respir J 2002; 20: Suppl. 38, 170s
Year: 2002

In vitro and in vivo modulation of NADPH oxidase activity and reactive oxygen species production in human neutrophils by a1-antitrypsin
Source: ERJ Open Res, 7 (4) 00234-2021; 10.1183/23120541.00234-2021
Year: 2021



Intracellular thioredoxin mediates inflammatory activation of an alveolar epithelial cell line through activation of NF-κB
Source: Eur Respir J 2003; 22: Suppl. 45, 37s
Year: 2003

The role of dual oxidase 1 in airway epithelial production of interleukin-8
Source: Annual Congress 2009 - Epithelial cell biology
Year: 2009

Cytosolic phospholipase A2 type IVβ induces interleukin – 8 and cyclooxygenase -2 gene expression but does not influence IL-16 and heme oxygenase-1 transcription in human lung cells
Source: Annual Congress 2004 - Inflammation and remodelling in human lungs
Year: 2004


Statins suppress LPS-induced proinflammatory cytokine production from human bronchial epithelial cells
Source: Annual Congress 2009 - Epithelial cell biology
Year: 2009


Cytokine-induced production of eotaxin-3 by human lung epithelial cells is inhibited by levocetirizine
Source: Eur Respir J 2005; 26: Suppl. 49, 98s
Year: 2005

NADPH oxidase isoform 1 is expressed in lung tissue of ARDS patients and decreases hyperoxia-induced ROS production and cell death in pulmonary type II epithelial cells
Source: Annual Congress 2011 - Barrier functions in sepsis and acute lung injury
Year: 2011


Sodium sulfite enhances rhinovirus-induced chemokine production in airway epithelial cells
Source: Annual Congress 2012 - Airway infections in children: from risk factors to treatment
Year: 2012

IL-8 and COX-2 expression is regulated through cPLA2-derived arachidonate metabolites in human lung cells
Source: Annual Congress 2003 - Intracellular signalling and regulation of cytokine production
Year: 2003


Nitrosoglutathione reductase inhibition in the airway epithelium may contribute to lung cancer risk
Source: Annual Congress 2011 - Biomarkers and other new methods for lung cancer
Year: 2011