Endothelin-1 activates pro-inflammatory signalling pathway via destinct p38MAPK isoforms resulting in downregulation of nuclear p27kip1 Source: Annual Congress 2009 - Airway cell biology Year: 2009
Transmission of muscarinic receptor mediated proliferative effects in human lung fibroblasts involves ERK-MAP kinase, but not PI-3 kinase and Rho-kinase pathway Source: Annual Congress 2007 - Miscellaneous pulmonary pharmacology Year: 2007
Inhibition of VEGF blocks the activation of TGF-β1 through a PI3K/Akt signaling pathway in allergic airway disease of mice Source: Annual Congress 2007 - Current issues in airway physiology, pharmacology and monitoring Year: 2007
Autocrine secretion of bradykinin prevents alveolar type II cells from mechanical stretch-induced apoptosis by activation – role of PI3K and Akt Source: Annual Congress 2008 - Border patrol: the alveolar barrier in lung injury Year: 2008
Insulin-dependent PI3-Kinase/Akt and ERK signaling pathways inhibit TLR3-mediated HBEC apoptosis Source: Annual Congress 2011 - Recent developments in COPD Year: 2011
Toll-like receptor stimulation induces airway hyperresponsiveness to bradykinin, an effect mediated by JNK and NF-κB signaling pathways Source: Eur Respir J 2005; 26: Suppl. 49, 732s Year: 2005
Glucocorticoids promote TGF-β signalling in lung fibroblasts by upregulating ligand and receptor expression, and uncoupling negative-feedback inhibition Source: Annual Congress 2010 - Recent developments of molecular pathology and functional genomics in non-neoplastic and neoplastic lung diseases Year: 2010
Angiotensin II and hypoxia synergistically induce proliferation in pulmonary artery fibroblasts by a PI-3K and PKC-signaling pathway through HIF-1 a and upregulation of angiotensin II-receptors type I Source: Eur Respir J 2002; 20: Suppl. 38, 378s Year: 2002
BMP-Smad1 target gene Wnt inhibitory factor 1 (WIF1) coordinates BMP and Wnt signaling activities in regulating lung development in vivo Source: Annual Congress 2010 - New mechanisms in lung development, acute and chronic lung diseases Year: 2010
Differential role of EPAC and PKA in the transduction of cAMP-mediated inhibition of human lung fibroblast proliferation and collagen synthesis Source: Annual Congress 2009 - Pathological remodelling in chronic lung disease: from epithelial-mesenchymal transition to cellular activation Year: 2009
6-aminonicotinamide ameliorates pulmonary fibrosis by suppressing the TGF-beta1 activated Smad signalling pathway Source: Virtual Congress 2020 – Translational therapeutic advances Year: 2020
In addition to mTOR and JAK/STAT, NLRP3 inflammasome is another key pathway activated in sarcoidosis Source: Eur Respir J, 55 (3) 2000149; 10.1183/13993003.00149-2020 Year: 2020
Anti-tussive effects of FAAH inhibition: The role of endocannabinoids and downstream signalling pathways in the inhibition of vagal sensory nerve activation Source: International Congress 2015 – Novel treatments for cough, asthma, COPD and bronchiectasis Year: 2015
AMPK signalling regulates Nrf2 localization and activity via sirtuins in a monocytic cell line Source: Annual Congress 2011 - Recent developments in COPD Year: 2011
Stimulation of NOD1 induces RIP2, TAK1 and p38 MAPK dependent pro-inflammatory signalling in human lung microvascular endothelial cells Source: Annual Congress 2011 - Mechanisms of acute lung injury and mesenchymal cell treatment Year: 2011
Corticosteroids reduce pro-inflammatory cytokine expression in airway smooth muscle cells via upregulation of MAPK phosphatase-1 and inhibition of p38 MAPK signalling Source: Eur Respir J 2005; 26: Suppl. 49, 713s Year: 2005
TLR4 signaling potentiates airway secretion from the swine submucosal gland via NO/cGMP/cGK pathway Source: Annual Congress 2012 - Cellular signalling mechanisms in the airways Year: 2012
Involvement of NFkB activation and c-JUN phosphorylation in bronchial epithelial cells by CD-40-CD40L pathway Source: Eur Respir J 2002; 20: Suppl. 38, 573s Year: 2002
G-protein mediated EGFR transactivation induces mucin production Source: Annual Congress 2003 - Cellular and molecular mechanisms in epithelium injury and repair Year: 2003
Leptin activates the JAK/STAT signaling pathway in bronchial and alveolar epithelial cells Source: Eur Respir J 2006; 28: Suppl. 50, 338s Year: 2006