Soluble guanylate cyclase stimulation: an emerging option in pulmonary hypertension therapy

Ghofrani H. A., Grimminger, F.

Source: Eur Respir Rev 2009; 18: 35-41
Journal Issue: March 2009 - 18 (111)
Disease area: Pulmonary vascular diseases

Congress or journal article abstractPDF journal article, handout or slides

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
Ghofrani H. A., Grimminger, F.. Soluble guanylate cyclase stimulation: an emerging option in pulmonary hypertension therapy. Eur Respir Rev 2009; 18: 35-41

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Riociguat: an upcoming therapy in chronic thromboembolic pulmonary hypertension?
Source: Eur Respir Rev 2009; 19: 68-71
Year: 2010



First acute haemodynamic study of soluble guanylate cyclase stimulator riociguat in pulmonary hypertension
Source: Eur Respir J 2009; 33: 785-792
Year: 2009



Riociguat for interstitial lung disease and pulmonary hypertension: a pilot trial
Source: Eur Respir J 2013; 41: 853-860
Year: 2013



Expression and function of soluble guanylate cyclase in pulmonary arterial hypertension
Source: Eur Respir J 2008; 32: 881-891
Year: 2008



Pharmacokinetics of the soluble guanylate cyclase stimulator riociguat in individuals with renal impairment
Source: Annual Congress 2013 –Pulmonary circulation: clinical treatment
Year: 2013

RESPITE: Riociguat in pulmonary arterial hypertension patients with an inadequate response to phosphodiesterase type 5 inhibitors
Source: International Congress 2016 – Clinic of pulmonary hypertension
Year: 2016


Improvement of exercise capacity in monocrotaline induced pulmonary hypertension by the phosphodiesterase inhibitor Vardenafil
Source: Annual Congress 2006 - Signalisation in the pulmonary vasculature: new pathways and wrong signals
Year: 2006


Current medical therapies in pulmonary arterial hypertension
Source: Eur Respir Mon 2012; 57: 26-41
Year: 2012


Iloprost for pulmonary vasodilator testing in idiopathic pulmonary arterial hypertension
Source: Eur Respir J 2009; 33: 1354-1360
Year: 2009



The use of combination therapy in pulmonary arterial hypertension: new developments
Source: Eur Respir Rev 2009; 18: 148-153
Year: 2009



Effects of a soluble guanylate cyclase stimulator, BAY 41-8543, upon right ventricular function in experimental pulmonary embolism
Source: Annual Congress 2012 - Pulmonary circulation: basic mechanisms, animal models and experimental treatments
Year: 2012


Goal-oriented treatment and combination therapy for pulmonary arterial hypertension
Source: Eur Respir J 2005; 26: 858-863
Year: 2005



Combination therapy with bosentan and sildenafil in idiopathic pulmonary arterial hypertension
Source: Eur Respir J 2004; 24: 1007-1010
Year: 2004



Effects of iloprost and the phosphodiesterase inhibitor tolafentrine on pulmonary vascular remodelling in chronic experimental pulmonary hypertension
Source: Eur Respir J 2003; 22: Suppl. 45, 20s
Year: 2003

RESPITE: switching to riociguat in pulmonary arterial hypertension patients with inadequate response to phosphodiesterase-5 inhibitors
Source: Eur Respir J, 50 (3) 1602425; 10.1183/13993003.02425-2016
Year: 2017



Combination of bosentan with epoprostenol in pulmonary arterial hypertension: BREATHE-2
Source: Eur Respir J 2004; 24: 353-359
Year: 2004



Phosphodiesterase 1 upregulation in pulmonary arterial hypertension – target for anti-remodeling therapy
Source: Eur Respir J 2006; 28: Suppl. 50, 159s
Year: 2006

Pulmonary hypertension in COPD
Source: Eur Respir Mon 2013; 59: 189-205
Year: 2013


Bosentan does not improve pulmonary hypertension and lung remodeling in heart failure
Source: Eur Respir J 2011; 37: 578-586
Year: 2011



A soluble guanylate cyclase stimulator, BAY 41-8543, preserves pulmonary artery endothelial function in experimental pulmonary embolism
Source: Annual Congress 2013 –Pulmonary circulation: animal models and experimental treatments
Year: 2013