Double blind randomised placebo controlled study of effect of inhalation of (72% O2 and 28% helium) on perception of methacholine induced breathlessness in asthma

A. H. Mansur, S. Manney, J. G. Ayres (Birmingham, Aberdeen/Scotland, United Kingdom)

Source: Annual Congress 2008 - Recent advances in the treatment and pathogenesis of pulmonary diseases
Session: Recent advances in the treatment and pathogenesis of pulmonary diseases
Session type: E-Communication Session
Number: 4276
Disease area: Airway diseases

Congress or journal article abstractE-poster

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
A. H. Mansur, S. Manney, J. G. Ayres (Birmingham, Aberdeen/Scotland, United Kingdom). Double blind randomised placebo controlled study of effect of inhalation of (72% O2 and 28% helium) on perception of methacholine induced breathlessness in asthma. Eur Respir J 2008; 32: Suppl. 52, 4276

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
The effect of high dose N-acetylcysteine (1200mg daily) on airway function and airway trapping in COPD patients — A double blinded randomized placebo controlled trial
Source: Annual Congress 2012 - COPD treatments: efficacy and safety
Year: 2012


Randomized, double blind, double dummy, placebo-controlled trial designed for comparing the effectiveness of formoterol (Foradil®) Aerolizer® and ipatropium bromide plus nebulized fenoterol (Berodual®) in asthma patients with ages ranging between 5 and 12 years who suffer acute asthma
Source: Annual Congress 2010 - Managing asthma and allergic disease in children
Year: 2010

Paracetamol increases airway resistance in stable asthmatics: A double blind, randomized, placebo controlled study
Source: Annual Congress 2010 - New or old physiological parameters in chronic airway disorders?
Year: 2010


A double-blind double dummy randomised placebo-controlled cross-over design clinical trial of formoterol delivered by two different dry powder devices in prevention of bronchoconstriction induced by methacholine in mild to moderate persistent asthma in adult patients
Source: Annual Congress 2009 - Airway hyperresponsiveness: mechanism and assessment
Year: 2009

A randomised, 4-way crossover study to examine the lung pharmacodynamic effects of single inhaled doses of tiotropium (18 μg), salmeterol (50 μg), tiotropium (18 μg) and salmeterol (50 μg) and placebo using whole body plethysmography in healthy subjects
Source: Annual Congress 2010 - Drug delivery and pharmacokinetics I
Year: 2010


Inhaled corticosteroids in patients with mild to moderate COPD with and without airway hyperresponsiveness to mannitol: A randomized placebo controlled trial
Source: Annual Congress 2011 - Biomarkers and exacerbations of asthma and COPD
Year: 2011


Fixed combination of glycopyrrolate and formoterol MDI (GFF-MDI) demonstrates superior inspiratory capacity (IC) compared to tiotropium DPI (Tio) following 7 days dosing, in a randomized, double-blind, placebo-controlled phase 2b study in patients with COPD
Source: Annual Congress 2011 - Bronchodilators in asthma and COPD
Year: 2011

The effect of salt room treatment on bronchial hyperresponsiveness in asthmatics: a randomised controlled trial
Source: Eur Respir J 2005; 26: Suppl. 49, 505s
Year: 2005

The TRIFLOW study; A randomised, cross-over study evaluating the effects of inhaled beclometasone/formoterol/glycopyrronium (BDP/F/G) on hyperinflation in COPD
Source: Virtual Congress 2020 – Clinical studies of COPD: combination inhalers and much more
Year: 2020


Randomized clinical trial (RCT) comparing formoterol vs. salbutamol plus ipratropium bromide in the treatment of acute asthma exacerbation (AE) at emergency room (ER)
Source: Eur Respir J 2005; 26: Suppl. 49, 503s
Year: 2005

Double blind, placebo controlled crossover study in COPD patients to assess the acute effect of budesonide/formoterol using HRCT and lung function tests
Source: Annual Congress 2011 - Biomarkers and exacerbations of asthma and COPD
Year: 2011


The effect of 3% and 6% hypertonic saline in viral bronchiolitis: a randomised controlled trial
Source: Eur Respir J 2014; 44: 913-921
Year: 2014



Effects of montelukast 10 mg O.D or placebo on blood ROS levels in current smokers: a controlled, randomised, double blind-study
Source: Eur Respir J 2003; 22: Suppl. 45, 101s
Year: 2003

The effect of montelukast added to steroid on airway function as compared with steroid alone and placebo: a single blind, controlled study in acute asthma
Source: Eur Respir J 2001; 18: Suppl. 33, 263s
Year: 2001

Effect of inhaled vaporized cannabis on dynamic airway function, breathlessness and exercise intolerance in adults with advanced COPD: A randomized controlled trial
Source: International Congress 2018 – New methods and concepts in tests of lung and respiratory muscle function
Year: 2018

Inhaled mannitol improves lung function assessed by forced oscillation in a placebo controlled trial in patients with bronchiectasis
Source: Eur Respir J 2004; 24: Suppl. 48, 470s
Year: 2004

Oxygen compared to air driven nebulisers for acute exacerbations of COPD: a randomised controlled trial.
Source: International Congress 2017 – COPD management
Year: 2017


Montelukast and steroid effects on airway function compared with steroid alone and placebo: a single blind, controlled study in asthmatic school children
Source: Eur Respir J 2003; 22: Suppl. 45, 132s
Year: 2003

Short-term effect of a single dose of inhaled procaterol on exercise performance in COPD: a randomized, double blind, placebo-controlled, crossover trial
Source: Annual Congress 2008 - Physiological response to exercise performance
Year: 2008


A randomized, double blind, cross-over study to investigate the pharmacodynamic equivalence of salbutamol administered via a new HFA134 inhaler versus Evohaler in mild stable asthmatics
Source: Eur Respir J 2006; 28: Suppl. 50, 210s
Year: 2006