Histone deacetylase activity is reduced in COPD. Modulation by theophylline Source: Eur Respir J 2003; 22: Suppl. 45, 4s Year: 2003
Decreased histone deacetylase activity in COPD Source: Annual Congress 2008 - Epigenetic modifications in lung disease Year: 2008
Effect of low-dose theophylline plus beclometasone on lung function in smokers with asthma: a pilot study Source: Eur Respir J 2009; 33: 1010-1017 Year: 2009
Effect of carbocysteine lysine salt on frequency of exacerbations in COPD patient treated with or without inhaled steroids Source: International Congress 2016 – In-patient and out-patient COPD management Year: 2016
microRNA-223 suppresses histone deacetylase 2 in chronic obstructive pulmonary disease Source: International Congress 2015 – Latest news on miRNAs in pulmonary research Year: 2015
Cilomilast decreases exacerbations and maintains lung function in patients with poorly reversible COPD Source: Eur Respir J 2004; 24: Suppl. 48, 88s Year: 2004
Roflumilast, an oral, once-daily PDE4 inhibitor, improves lung function and reduces exacerbation rates in patients with COPD Source: Eur Respir J 2004; 24: Suppl. 48, 21s Year: 2004
Smoking cessation but not inhaled corticosteroids (ICS) can increase histone deacetylase 2 (HDAC2)] in COPD Source: Annual Congress 2010 - Novel mechanisms in COPD Year: 2010
Inflammatory markers and HDAC activity in induced sputum of smokers and COPD patients Source: Eur Respir J 2007; 30: Suppl. 51, 586s Year: 2007
Corticosteroid sensitivity in patients with chronic obstructive pulmonary disease is restored by theophylline Source: Annual Congress 2005 - Therapeutic options for COPD: present and future Year: 2005
Hypoxia associated with increased systemic concentrations of MPO and NE during exacerbations of COPD Source: International Congress 2015 – New insights into lung disease pathogenesis Year: 2015
Stable COPD: predicting benefit from high-dose inhaled corticosteroid treatment Source: Eur Respir J 2006; 27: 964-971 Year: 2006
Formoterol demonstrates bronchodilator efficacy in patients with reversible or poorly reversible chronic obstructive pulmonary disease (COPD), regardless of concomitant corticosteroid use Source: Eur Respir J 2001; 18: Suppl. 33, 177s Year: 2001
Histone deacetylase activity and gene expression in COPD patients Source: Eur Respir J 2001; 18: Suppl. 33, 316s Year: 2001
Outcome of COPD exacerbations treated with and without oral steroids in relation to airway and systemic inflammation Source: Eur Respir J 2005; 26: Suppl. 49, 283s Year: 2005
Changes in DNA methylation after corticosteroids treatment in COPD patients Source: Virtual Congress 2020 – Cutting edge science: novel molecules and mechanisms of airway diseases Year: 2020
Clinically important deteriorations in COPD as a measure of response to dual and mono bronchodilator therapy with and without inhaled corticosteroids Source: International Congress 2015 – New data on established treatments for COPD Year: 2015
The role of histone deacetylase 9 in the imbalance of Th17/Treg in bronchial asthma Source: Annual Congress 2012 - Mechanisms of asthma Year: 2012
Effect of cigarette smoke extract (CSE) on histone acetylation of lung fibroblasts in vitro compared to histone acetylation in patients with lung emphysema Source: Eur Respir J 2006; 28: Suppl. 50, 583s Year: 2006